Results 131 to 140 of about 4,154,097 (280)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Reserves’ influence on South Africa’s total domestic debt: evidence from GFECRA
Cogent Economics & FinanceThis research tackles a gap in existing literature by offering empirical insights into the effectiveness of utilizing the Gold and Foreign Exchange Contingency Reserve Account (GFECRA) in overseeing total domestic debt, thereby enhancing our ...
Eugene Msizi Buthelezi
doaj +1 more source
A revision of cervid phylogeny using a total evidence approach [PDF]
, 2013 Asher, Robert J. +4 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Revista Colombiana de Cirugía, 2012 Introducción. La tiroidectomía total es el procedimiento quirúrgico más común practicado en el cuello. Existen recomendaciones basadas en la evidencia que pueden causar un impacto en el costo del procedimiento.
Álvaro Sanabria +4 more
doaj
Total-evidence analyses of Crustacean evolution
, 2019 Crustaceans are an ecologically and economically significant group of arthropods, being hyperdiverse and spanning marine, freshwater, and terrestrial environments. Many crustaceans are ecosystem engineers, bioindicators, and keystone species, which are integral in maintaining ecosystem health and function.
openaire +1 more source
, 2018 Calyptrates are a megadiverse, actively radiating, group of dipterans, which are widely spread and abundant in nearly all terrestrial environments. Despite huge diversity and economic importance, their phylogeny is far from resolved.
Gisondi, S.
core
The role of histone modifications in transcription regulation upon DNA damage
FEBS Letters, EarlyView.This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Can All-Accuracy Accounts Justify Evidential Norms? [PDF]
, 2018 Some of the most interesting recent work in formal epistemology has focused on developing accuracy-based approaches to justifying Bayesian norms. These approaches are interesting not only because they offer new ways to justify these norms, but because ...
Meacham, Christopher J. G.
core