Results 81 to 90 of about 7,196,264 (196)

Lactate‐Induced K370 Lactylation of STING Inhibits STING‐TBK1 Signaling and Dampens Anti‐Tumor Immunity

Advanced Science, EarlyView.
Lactate accumulation in glioblastoma drives lactylation of STING at lysine 370, a primate‐conserved residue. K370 lactylation weakens STING‐TBK1 binding, destabilizes STING, and disrupts ER‐to‐Golgi trafficking, blunting type I interferon signaling. LDHA inhibition reverses K370 lactylation and improves the antitumor efficacy of STING agonism combined ...
Yueyao Wu, Jingzhe Wang, Xu Chen, Yuntong Yang, Ping Wei, Han Xie, Honghao Wang, Chunyu Zhang, Siyi Xu, Qi Wang, Chunlong Zhong, Jing Zhang   +11 more
wiley   +1 more source

The Effect of Current Ratio, Debt to Equity Ratio, Total Asset Turnover, and Return on Assets on Firm Value

AJARCDE (Asian Journal of Applied Research for Community Development and Empowerment)
In this study, we will look at the food and beverage subsector companies listed on the Indonesia Stock Exchange for the period of 2023–2024 to see how the Current Ratio (CR), Debt to Equity Ratio (DER), Total Asset Turnover (TATO), and Return on Assets (ROA) affect company value, as measured by Tobin's Q.
Masruro Masruro, Lilik Mardiana
openaire   +1 more source

Pengaruh Total Asset Turnover, Inventory Turnover, Receivable Turnover Terhadap Pertumbuhan Laba Pada Perusahaan Sub Sektor Perdagangan Eceran Yang Terdaftar Di Bursa Efek Indonesia Periode 2017-2021

, 2023
Pertumbuhan laba merupakan kenaikan laba atau penurunan laba per tahun yang dapat digunakan untuk menilai bagaimana perkembangan kinerja suatu perusahaan.
FITRIANA, IDA
core  

Bioinspired Porphyrin‐Based Catalysts From Temporospatial Confined Frameworks for Ultrafast Removal of Sulfaclozine

Advanced Science, EarlyView.
We report the rational design of artificial photocatalysts with asymmetrically coordinated dual‐metal centers and a tailored microenvironment, broadly applicable strategy is established for the synthesis of multivariate zirconium‐based metal–organic frameworks, offering a platform for precisely tuning active‐site configurations to optimize ...
Yuxin Lu, Yu‐Hang Li, Zhiyi Sun, Fanke Tong, Zelin Li, Sheng Wang, Shangkun Pei, Yi Li, Xiyan Xu, Chong‐Chen Wang, Bo Wang, Xiang Li   +11 more
wiley   +1 more source

Asset Management Section

, 2015
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on May 22, 2015)."The Asset ...

core  

Targeting β2‐Adrenergic Receptor Stability With Lycorine Reveals a Host‐Directed Pathway for Antiviral Defense Against Poxviruses

Advanced Science, EarlyView.
Chronic stress drives autophagy‐mediated β2‐AR degradation, impairing antiviral immunity and promoting poxvirus lethality. Lycorine directly stabilizes β2‐AR to restore host defense, suppress excessive inflammation and improve survival. ABSTRACT Psychological stress is a pervasive yet poorly understood modulator of infectious disease outcomes. Here, we
Xin Zhang, Shuqin Xu, Zixuan Zhang, Chenwen Wan, Xiaoqin Wang, Peihua Wang, Huini Yang, Tianxiao Huang, Yijia Yuan, Faiza Atique, Rui Yang, Yingli He, Zhijun Liu   +12 more
wiley   +1 more source

Phase Separation, Material State, and Condensate Fate in Mammalian Autophagy

Advanced Science, EarlyView.
ABSTRACT Biomolecular phase separation has emerged as a key organizing principle in macroautophagy (hereafter autophagy). In mammalian cells, phase‐separated condensates not only serve as substrates for selective degradation, but also act as dynamic platforms for cargo recognition, signaling integration, and autophagosome assembly.
Yuanqiang Lin, Mingran Dai, Enyong Dai, Rui Kang, Daniel J. Klionsky, Daolin Tang, Yu Sun, Ningning Lv, Junnan Jiang   +8 more
wiley   +1 more source

Pengaruh Struktur Aktiva, Debt to Asset Ratio, Total Asset Turnover dan Return On Asset terhadap Price Book Value

Jurnal Penelitian Ekonomi Akuntansi (JENSI)
This study aims to determine the effect of Asset Structure, Debt to Asset Ratio, Total Asset Turnover and Return On Asset on the Price Book Value in advertising, printing and media sub-sector companies listed on the Indonesian Stock Exchange for the 2018-2022 period. This research is a type of descriptive research with quantitative methods.
Amanda Sulistia, Priyambada Bagus Artanta   +1 more
openaire   +2 more sources

Targeting the NR1D1–IGF2BP2–V‐ATPase Axis With Hybrid Nanovesicles Restores Macrophage Rhythms to Reverse Sepsis‐Induced Immunosuppression

Advanced Science, EarlyView.
Sepsis disrupts immune‐cell rhythms and weakens bacterial clearance. Biomimetic nanovesicles combining erythrocyte and inflammation‐activated macrophage membranes deliver siNR1D1 to dysfunctional macrophages, restoring the NR1D1–IGF2BP2–V‐ATPase pathway, circadian regulation, phagolysosomal acidification, and antimicrobial defense.
Lang Chen, Wenyi Lin, Lang Jiang, Xuehui Gao, Chenyan Yu, Jili Han, Zhenping Liu, Xuefeng Li, Mei He, Chang Li, Qilan Li, Chaoying Song, Jiqian Xu, You Shang   +13 more
wiley   +1 more source

PENGARUH CURRENT RATIO (CR), DEBT TO ASSET RATIO (DAR), TOTAL ASSET TURNOVER (TATO) TERHADAP RETURN ON ASSET (ROA)

Journal Of Communication Education
Penelitian ini bertujuan untuk mengetahui pengaruh current ratio¸debt to asset ratio dan total asset turnover terhadap return on asset pada PT. Unilever Indonesia Tbk periode 2006-2022. Penelitian ini menggunakan metode kuantitatif. Metode analisis data yang digunakan berupa metode deskriptif, metode kuantitatif terdiri dari uji Asumsi klasik, Analisis
Rachma Nadhila Sudiyono, Ria Hartati
openaire   +1 more source