Results 61 to 70 of about 41,334 (304)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
An Improved Upper Bound on Neighbor Expanded Sum Distinguishing Index
Discussiones Mathematicae Graph Theory, 2020 A total k-weighting f of a graph G is an assignment of integers from the set {1, . . . , k} to the vertices and edges of G. We say that f is neighbor expanded sum distinguishing, or NESD for short, if Σw∈N(v) (f(vw) + f(w)) differs from Σw∈N(u)(f(uw) + f(
Vučković Bojan
doaj +1 more source
Total colorings and list total colorings of planar graphs without intersecting 4-cycles
Discrete Mathematics, 2009 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Liu, Bin +3 more
openaire +2 more sources
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Facial [r,s,t]-Colorings of Plane Graphs
Discussiones Mathematicae Graph Theory, 2019 Let G be a plane graph. Two edges are facially adjacent in G if they are consecutive edges on the boundary walk of a face of G. Given nonnegative integers r, s, and t, a facial [r, s, t]-coloring of a plane graph G = (V,E) is a mapping f : V ∪ E → {1, . .
Czap Július +3 more
doaj +1 more source
Total variant of well known graph coloring game is considered. We determine exact values of total game chromatic number for some classes of graphs and show show the strategie for first player to win the game. We also show relation between total game coloring number and game coloring index.
Bartnicki, Tomasz, Miechowicz, Zofia
openaire +2 more sources
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A Sufficient Condition for Planar Graphs of Maximum Degree 6 to be Totally 7-Colorable
Discrete Dynamics in Nature and Society, 2020 A total k-coloring of a graph is an assignment of k colors to its vertices and edges such that no two adjacent or incident elements receive the same color.
Enqiang Zhu, Yongsheng Rao
doaj +1 more source