Results 231 to 240 of about 756,421 (298)

AI‐Based D‐Amino Acid Substitution for Optimizing Antimicrobial Peptides to Treat Multidrug‐Resistant Bacterial Infection

Advanced Science, EarlyView.
This study constructed the first D‐amino acid antimicrobial peptide dataset and developed an AI model for efficient screening of substitution sites, with 80% of candidate peptides showing enhanced activity. The lead peptide dR2‐1 demonstrated potent antimicrobial activity in vitro and in vivo, high stability, and low toxicity.
Yinuo Zhao, Qingzhou Kong, Haifan Gong, Lixiang Li, Jialu Fu, Boyao Wan, Peizhu Wang, Xiaojuan Li, Yue Wang, Jinghui Zhang, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +14 more
wiley   +1 more source

Prevalence and characteristics of metabolic dysfunction-associated steatohepatitis among pediatric patients in the MarketScan Databases. [PDF]

PLoS One
Peter-Marske KM, Zhang X, Wang T, Liu X, Fernandes G, Engel SS, Shankar R.   +6 more
europepmc   +1 more source

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

Psychological Flexibility as a Mediator Between Spiritual Coping and End-of-Life Care Attitudes in ICU Nurses: A Cross-Sectional Study. [PDF]

Nurs Crit Care
Wu R, Chen X, Li S, Zhu H, Wang L, Zhang H, Gong X, He X, Liu J.   +8 more
europepmc   +1 more source

Multi-omics provides functional insights and underscores practical challenges in assessing the composition and performance of a nitrifying microbial consortium. [PDF]

Appl Environ Microbiol
Smith DDN, Subasinghe RM, Kehoe C, Grégoire DS.   +3 more
europepmc   +1 more source

Passion, Motivation, and Well-Being in Young Footballers: A Systematic Review. [PDF]

Healthcare (Basel)
Braz D, Maia C, Gouveia É, Monteiro D, Couto N, Sarmento H.   +5 more
europepmc   +1 more source

Medicare Coding Changes and Reported Hernia Size.

JAMA
Hallway A, Isenberg E, Howard R, O'Neill S, Shao J, Schoel L, Rubyan M, Ehlers A, Telem D.   +8 more
europepmc   +1 more source

Psychological Distress and Health-Related Quality of Life in Romanian Adults with Diabetes Mellitus: A Cross-Sectional Study. [PDF]

Healthcare (Basel)
Bubulac L, Dobjanschi CG, Zivari M, Erena C, Tudor V, Spînu AD, Muşat GC, Bogdan-Andreescu CF, Cadar E, Albu CC.   +9 more
europepmc   +1 more source

Navigating extreme class imbalance in suicide risk prediction. [PDF]

Front Psychiatry
Kitchen C, Belouali A, Nestadt PS, Wilcox HC, Kharrazi H.   +4 more
europepmc   +1 more source