Results 41 to 50 of about 46,193 (265)

Advanced Encryption Standard (AES) 128 Bit untuk Keamanan Data Internet of Things (IoT) Tanaman Hidroponik

Jurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2020
One method of growing vegetables is to use hydroponics by utilizing water as the medium used. In this era of rapidly developing technology, one of which is Internet of Things (IoT) is a system between computers or objects that can connect and exchange ...
Roiya Ravida, Heru Agus Santoso
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Enzymatic One-Pot Hydrolysis of Extracted Sugar Beet Press Pulp after Solid-State Fermentation with an Engineered Aspergillus niger Strain

Fermentation, 2023
Extracted sugar beet press pulp (SBPP) is a promising agricultural residue for saccharification and further bioconversion. Combining solid-state fermentation of SBPP with engineered Aspergillus niger for enzyme production followed by hydrolysis of ...
Melanie Knesebeck, Dominik Schäfer, Kevin Schmitz, Marcel Rüllke, J. Philipp Benz, Dirk Weuster-Botz   +5 more
doaj   +1 more source

UTILIZING TOTAL DISSOLVED SOLIDS (TDS) SENSOR FOR DISSOLVED SOLIDS MEASUREMENT IN THE WATER

JISO : Journal of Industrial and Systems Optimization
Although industrialization and population growth seriously threaten clean water, which is necessary for life, they also cause significant pollution. Monitoring water quality, including Total Dissolved Solids (TDS), ensures health standards. TDS represents dissolved substances in water, affecting taste, safety, and usability. Recent sensor advancements,
Handandi Zukhruf Z, Hidayana Elmi, Setiawan Edy, Anda Iviana Juniani, Nugraha Anggara T, P. Amelia   +5 more
openaire   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Water quality assessment using WQI and zooplankton indicators in aquatic ecosystems: Insights from a correlation-based study

Cleaner Water
Since rivers provide freshwater to all rural and urban communities, it is necessary but difficult to monitor the river water quality. The goal of this study was to assess how water-quality parameters relate to zooplankton communities.
Sk Saruk Islam, Sudip Narayan Dhara, Sujoy Midya   +2 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Measurement of Total Dissolved Solids and Total Suspended Solids in Water Systems: A Review of the Issues, Conventional, and Remote Sensing Techniques

Remote Sensing, 2023
This study provides a comprehensive review of the efforts utilized in the measurement of water quality parameters (WQPs) with a focus on total dissolved solids (TDS) and total suspended solids (TSS). The current method used in the measurement of TDS and TSS includes conventional field and gravimetric approaches.
Godson Ebenezer Adjovu, Haroon Stephen, David James, Sajjad Ahmad   +3 more
openaire   +2 more sources

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

A geophysical and hydro physico-chemical study of the contaminant impact of a solid waste landfill (swl) in King Williams’ Town, Eastern Cape, South Africa

Open Geosciences, 2019
Electrical resistivity imaging (ERI) surveys and physico-chemical analysis were carried out on a solid waste landfill (SWL) in Eastern Cape, South Africa to assess the impact of leachate pollution on groundwater quality.
Mepaiyeda S., Baiyegunhi C., Madi K., Gwavava O.   +3 more
doaj   +1 more source