Results 91 to 100 of about 523 (191)

Lower Striatal and Cortical Calretinin Interneuron Density Associated With Altered Social Behavior in Cntnap2 Knockout Mice

open access: yesAutism Research, EarlyView.
ABSTRACT Variants in the CNTNAP2 gene, encoding the cell adhesion molecule CASPR2, have been identified as genetic risk factors for autism spectrum disorder (ASD). However, the mechanisms through which CNTNAP2 dysfunction alters circuit function remain unknown.
Krisztina Sáfár   +10 more
wiley   +1 more source

Multi‐Scale Hybrid Modeling to Predict Cell Culture Process With Metabolic Phase Transitions

open access: yesBiotechnology and Bioengineering, EarlyView.
ABSTRACT To advance understanding of cellular metabolism and reduce batch‐to‐batch variability in cell culture processes, this study introduces a multi‐scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell cultures undergoing metabolic phase transitions.
Keqi Wang, Sarah W. Harcum, Wei Xie
wiley   +1 more source

The extension of the taxon cycle model to island plants: insights from the Canarian vascular flora

open access: yesBiological Reviews, EarlyView.
ABSTRACT Taxon cycle models describe eco‐evolutionary patterns of lineage colonization, diversification, and decline across archipelagos, inferring an important role for competition amongst ecologically similar taxa in driving concurrent niche changes.
José María Fernández‐Palacios   +2 more
wiley   +1 more source

Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife

open access: yesBiological Reviews, EarlyView.
ABSTRACT Highly pathogenic avian influenza (HPAI) has become a critical threat to wildlife, shifting from a seasonal epizootic to a persistent, year‐round panzootic with global consequences. Here, we summarise the origin, evolutionary mechanisms, and expanding host range of the current H5N1 virus (clade 2.3.4.4b) and assess its impact on wildlife. Over
Ulrich Knief   +4 more
wiley   +1 more source

Signatures of the Anthropocene: Population Genomic Structure Detected in Pennsylvania Coyotes. [PDF]

open access: yesEcol Evol
Marshall CA   +15 more
europepmc   +1 more source

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