Results 141 to 150 of about 523 (191)

Robinow syndrome DVL1 variants disrupt morphogenesis and appendage formation in a Drosophila disease model

Developmental Dynamics, EarlyView.
Abstract Background Robinow syndrome is a rare developmental syndrome caused by variants in genes in Wnt signaling pathways. We previously showed that expression of patient variants in Dishevelled 1 (DVL1) in Drosophila and chicken models disrupts the balance of canonical and non‐canonical Wnt signaling.
Gamze Akarsu, Katja R. MacCharles, Kenneth Kin Lam Wong, Joy M. Richman, Esther M. Verheyen   +4 more
wiley   +1 more source

PRECISE-seq reveals disease-relevant TCR repertoires with phenotypic plasticity. [PDF]

J Exp Med
Liu S, Liang G, Yang Y, Shi Y, Dong L, Zhao Y, Mei B, Wang J, Lin F, Li Y, Dong W, Liu C, Cao Y, Han D, Chen PR, Xu MM.   +15 more
europepmc   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Biotic interactions explain seasonal dynamics of the alpine soil microbiome. [PDF]

ISME Commun
Fiore-Donno AM, Freudenthal J, Dahl MB, Rixen C, Urich T, Bonkowski M.   +5 more
europepmc   +1 more source

Secretopathies emerge as a new class of neurocristopathies

Developmental Dynamics, EarlyView.
Abstract Neural crest cells are a transient embryonic population of cells that give rise to a wide range of structures, including craniofacial cartilage and bone, peripheral neurons and glia, as well as components of the cardiac outflow tract, among others.
Amanda Teixeira, Cassandra Millet‐Boureima, Joshua A. Moore, Loydie A. Jerome‐Majewska   +3 more
wiley   +1 more source

Structure of Benthic Microbial Communities in the Northeastern Part of the Barents Sea. [PDF]

Microorganisms
Stroeva AR, Klyukina AA, Vidishcheva ON, Poludetkina EN, Solovyeva MA, Pyrkin VO, Gavirova LA, Birkeland NK, Akhmanov GG, Bonch-Osmolovskaya EA, Merkel AY.   +10 more
europepmc   +1 more source

Psychiatric Morbidity Is Overrepresented in Young Girls at High Risk of Developing Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Psychiatric comorbidity frequently presents in anorexia nervosa (AN). Yet, the premorbid mental health status is relatively unknown. The aim of this study was to map out psychiatric morbidity and psychopathology among girls at familial high risk (FHR) of developing AN, thereby detecting possible underlying vulnerabilities preceding ...
Karin Dahlin, Kajsa Järvholm, Jovanna Dahlgren, Elisabet Wentz   +3 more
wiley   +1 more source

Developing a macroecology for human‐altered ecosystems

Ecography, EarlyView.
Although anthropogenically‐induced ecological disruptions are fundamentally important in defining ecosystem properties, they are largely overlooked by macroecological theory. Anthropogenic disruptions and their effects are generally not comparable to one another, nor to disturbances that are part of natural disturbance regimes.
Erica A. Newman, Mark Q. Wilber, Alexandre Génin, Oriana E. Chafe, Henry F. Houskeeper, Steven Lee, Eric L. Berlow, John Harte   +7 more
wiley   +1 more source

Precarity in the Modes of Living: Proposing an Index for Studying Health Inequities at the Ecological Level in Colombia. [PDF]

Int J Environ Res Public Health
Santa Ramírez HA, Ramírez-Giraldo AF, Pilkington H, Borrell C, Otálvaro-Castro GJ.   +4 more
europepmc   +1 more source

Licensed Commoning and the Authoritarian Commons: Governing Participation in China's Community Gardens

Environmental Policy and Governance, EarlyView.
ABSTRACT China's environmental governance transition combines intensified vertical accountability and performance‐based management with expanding calls for public participation. However, despite growing demand for civic engagement, there remains limited understanding of how participatory environmental initiatives are structured and governed in practice.
Linjun Xie, Mengqi Shao, Gaohan Deng
wiley   +1 more source