Regional Total Electron Content Disturbance During a Meteorological Storm
AtmosphereThis study presents a comprehensive analysis of the impact of Storm Laura, which was observed over Europe and the Baltic Sea on 12 March 2020, on the thermosphere–ionosphere system.
Olga P. Borchevkina +9 more
doaj +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Ionosonde and GPS total electron content observations during the 26 December 2019 annular solar eclipse over Indonesia [PDF]
, 2023 Jiyo Harjosuwito +8 more
openalex +1 more source
Interplay between RNA‐protein interactions and RNA structures in gene regulation
FEBS Open Bio, EarlyView.Methodological advances in mapping transcriptome‐wide RNA‐protein interactions and RNA structures have started to uncover the potential of RNP conformations in gene regulation. Competing RNA–RNA, RNA‐protein and protein–protein interactions shape the compaction and function of RNPs throughout their lifetime and may provide novel therapeutic targets in ...
Jenni Rapakko +2 more
wiley +1 more source
Neustrelitz Total Electron Content Model for Galileo Performance: A Position Domain Analysis. [PDF]
Sensors (Basel), 2023 Gioia C, Angrisano A, Gaglione S.
europepmc +1 more source
Variations in the total electron content of the ionosphere at mid-latitudes during quiet sun conditions [PDF]
Faraday rotation effect on satellite signals used to determine ionospheric electron content at midlatitudes during quiet sun ...
Solomon, S. L.
core +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Complete Global Total Electron Content Map Dataset based on a Video Imputation Algorithm VISTA. [PDF]
Sci Data, 2023 Sun H +6 more
europepmc +1 more source
Processing Satellite Data for Slant Total Electron Content Measurements [PDF]
A method, system, and apparatus provide the ability to estimate ionospheric observables using space-borne observations. Space-borne global positioning system (GPS) data of ionospheric delay are obtained from a satellite.
Komjathy, Attila +3 more
core +1 more source