Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Total Factor Productivity growth, Technological Progress, and Efficiency Changes: Empirical Evidence from Canadian Manufacturing Industries [PDF]
As productivity (growth) appears to be the single most important determinant of a nation’s living standard or its level of real income over long periods of time, it is important to better understand the sources of productivity growth.
Mahamat Hamit-Haggar
core
Total Estimated Cost of Child Abuse & Neglect In The United States: Statistical Evidence [PDF]
, 2001 This data represents the first attempt to document the nationwide costs resulting from abuse and neglect. These costs can be placed in one of two categories: direct (those costs associated with the immediate needs of abused or neglected children) and ...
Suzette Fromm
core
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Can industrial robots boost carbon total factor productivity? – Evidence from China
Journal of Innovation & KnowledgeIndustrial robots are essential for improving productivity and optimizing resource allocation. They help to reduce dependence on traditional labor- and energy-intensive manufacturing methods.
Yu Ma, Yongqi Ma, Zijun Ding
doaj +1 more source
Constraints on narrow exotic states from K+p and K0_Lp scattering data
, 2004 We consider the effect of exotic S=+1 resonances Theta+ and Theta++ on K+p elastic scattering data (total cross section) and the process K0_Lp-->K0_Sp. Data near the observed Theta+(1540) are examined for evidence of additional states.
A. Bigi +17 more
core +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Contrasting supertree and total-evidence methods: the origin of the pterosaurs [PDF]
, 2008 Benton, Michael J., Hone, David W. E.
core +1 more source
Explaining local manufacturing growth in Chile : the advantages of sectoral diversity [PDF]
This paper investigates whether the agglomeration of economic activity in regional clusters affects long-run manufacturing total factor productivity growth in an emerging market context.
Almeida, Rita, Fernandes, Ana M.
core