Results 81 to 90 of about 23,969,272 (337)

Prognostic Impact of Treatment Modalities, Including Targeted Compartmental Radio‐Immunotherapy, in a Cohort of Neuroblastoma Patients With CNS Metastases at Relapse

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction Neuroblastoma (NB) with central nervous system (CNS) metastases is rare at diagnosis, but occurs more often during relapse/progression. Patients with CNS metastases face a dismal prognosis, with no standardized curative treatment available.
Vicente Santa‐Maria Lopez   +13 more
wiley   +1 more source

Management of instability after primary total knee arthroplasty: an evidence-based review

open access: yesJournal of Orthopaedic Surgery and Research, 2021
Background Instability is one of the most common reasons for revision after a total knee replacement. It accounts for 17.4% of all single-stage revision procedures performed in the UK National Joint Registry.
Talal Al-Jabri   +3 more
doaj   +1 more source

Optimal time travel in the Godel universe

open access: yes, 2011
Using the theory of optimal rocket trajectories in general relativity, recently developed in arXiv:1105.5235, we present a candidate for the minimum total integrated acceleration closed timelike curve in the Godel universe, and give evidence for its ...
C. Misner   +13 more
core   +1 more source

The neighbourhood physical environment and active travel in older adults : a systematic review and meta-analysis [PDF]

open access: yes, 2017
BACKGROUND: Perceived and objectively-assessed aspects of the neighbourhood physical environment have been postulated to be key contributors to regular engagement in active travel (AT) in older adults.
Andrea Nathan   +5 more
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults [PDF]

open access: yes, 2015
Background Total thyroidectomy (TT) and subtotal thyroidectomy (ST) are worldwide treatment options for multinodular non-toxic goitre in adults.
Arezzo, Alberto   +9 more
core   +2 more sources

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher   +8 more
wiley   +1 more source

Rural e-commerce and agricultural total factor productivity: Evidence from China

open access: yesAgricultural Economics (AGRICECON)
Employing the Comprehensive Demonstration of E-commerce in Rural Areas (CDERA) policy as a quasi-natural experiment, this paper explores the impact of rural e-commerce development on agricultural total factor productivity (ATFP) and its underlying ...
Jialong Zheng   +3 more
doaj   +1 more source

Finding Evidence for Massive Neutrinos using 3D Weak Lensing

open access: yes, 2008
In this paper we investigate the potential of 3D cosmic shear to constrain massive neutrino parameters. We find that if the total mass is substantial (near the upper limits from LSS, but setting aside the Ly alpha limit for now), then 3D cosmic shear ...
A. Cooray   +12 more
core   +1 more source

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