Results 261 to 270 of about 732,396 (308)

Referral and management patterns for paediatric otorrhoea across primary and secondary care: a multicentre retrospective cohort study. [PDF]

Prim Health Care Res Dev
Heward E, Collingwood A, Jeffry F, Agrawal S, Jayaram S, Ashcroft DR, Hay AD, Nichani JR, Bruce IA.   +8 more
europepmc   +1 more source

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Environmental dependence of visible anthocyanin accumulation mediated by the <i>CmMYB6-CmbHLH2</i> complex. [PDF]

Front Plant Sci
Deng Q, Zhu X, Liu S, Wang J, Zhou Z, Yu X, Liao Z, Xu L, Li Y, Xiang L.   +9 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Mitochondria limit coenzyme Q export under cholesterol biosynthetic stress. [PDF]

J Cell Biol
Ndoci M, Bhattacharya S, Agrawal I, Hinze Y, Lemke K, Schumacher AL, Uijttewaal E, Elling U, Lawo S, Giavalisco P, Langer T, Deshwal S.   +11 more
europepmc   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong, Sebastian Díaz‐Pérez, Kevin Navin Sheth, Jang‐Ho Cha, C. J. Malanga, Patricia G. M. Wagner, Nicole Pezous, Aurelie Hanin, Kyle B. Walsh, H. E. Hinson, Lauren Hachmann Sansing   +10 more
wiley   +1 more source

On the optimization of copy number variations representation in pangenome graphs. [PDF]

Front Bioinform
Coggi M, Basile L, Branchini B, Amodeo G, Di Donato GW, Santambrogio MD.   +5 more
europepmc   +1 more source

Multiplex networks-based directed graph neural network for cancer driver gene identification. [PDF]

PLoS Comput Biol
Li P, Xie M.
europepmc   +1 more source

Cell-type-specific actions of carnosic acid against <i>Porphyromonas gingivalis</i>-induced proliferation in liver cancer cells. [PDF]

J Oral Microbiol
Wang T, Chiba T, Ishikawa T, Kuroda H, Kakisaka K.   +4 more
europepmc   +1 more source

Active ROP2 triggers leaf senescence and orchestrates the growth-senescence trade-off under nitrogen starvation. [PDF]

Plant Signal Behav
Zhang T, Ye H, Zhang Y, Wang J, Wang J, Lixiang S, Lin Z, Xiong Y, Liu Y.   +8 more
europepmc   +1 more source