Results 181 to 190 of about 80,673 (317)

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden   +3 more
wiley   +1 more source

Musculoskeletal health among adults with cerebral palsy: A systematic review

open access: yesDevelopmental Medicine &Child Neurology, EarlyView.
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan   +11 more
wiley   +1 more source

Balancing Safety and Efficacy: Uncemented Versus Cemented Total Hip Arthroplasty in the Elderly. [PDF]

open access: yesJ Am Acad Orthop Surg Glob Res Rev
Carangelo RJ   +3 more
europepmc   +1 more source

Perioperative Outcomes in Factor XI Deficiency: A Systematic Review

open access: yesHaemophilia, EarlyView.
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni   +6 more
wiley   +1 more source

Clin‐STAR Corner: Practice Changing Advances at the Interface of Artificial Intelligence/Machine Learning and Geriatrics

open access: yesJournal of the American Geriatrics Society, EarlyView.
ABSTRACT Artificial intelligence (AI) methods, including machine learning (ML), are transforming healthcare by enabling personalized interventions that integrate multimodal data to support rehabilitation, preventive care, and remote monitoring. Despite their broad potential, older adults remain underrepresented in model development, raising concerns ...
Tue T. Te   +3 more
wiley   +1 more source

Incidence and Severity of Nurse‐Sensitive Adverse Events in Older Adults After Physical Trauma: A Medical Record Review

open access: yesJournal of Clinical Nursing, EarlyView.
ABSTRACT Aim This study aimed to investigate the incidence and characteristics of nursing‐sensitive adverse events (NSAEs) in older adults (≥ 65 years) hospitalised with traumatic injuries, and to explore associations with frailty, demographic factors, injury characteristics and hospital‐related factors.
Hanna Järbrink   +4 more
wiley   +1 more source

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