Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden +3 more
wiley +1 more source
Hip Arthroscopy After Total Hip Arthroplasty: A Current Review of Indications, Techniques, and Outcomes. [PDF]
Harrington J +3 more
europepmc +1 more source
Musculoskeletal health among adults with cerebral palsy: A systematic review
Abstract Aim To describe the burden of, and investigate prognostic factors for, osteoarthritis, osteopenia and/or osteoporosis, spondylosis, and fracture, and to investigate the effectiveness of protocols for monitoring musculoskeletal disorders and interventions for managing osteoarthritis in adults with cerebral palsy (CP).
Jennifer M. Ryan +11 more
wiley +1 more source
Balancing Safety and Efficacy: Uncemented Versus Cemented Total Hip Arthroplasty in the Elderly. [PDF]
Carangelo RJ +3 more
europepmc +1 more source
Perioperative Outcomes in Factor XI Deficiency: A Systematic Review
ABSTRACT Background Congenital factor XI (FXI) deficiency has a variable bleeding phenotype, and FXI activity alone does not predict perioperative bleeding. Management practices remain heterogeneous, and available evidence derives from case reports, small case series, and retrospective cohorts.
Zainab Al‐Housni +6 more
wiley +1 more source
Trends and Outcomes in Outpatient Revision Total Hip Arthroplasty: A Retrospective Matched Cohort Study. [PDF]
Lin C +5 more
europepmc +1 more source
ABSTRACT Artificial intelligence (AI) methods, including machine learning (ML), are transforming healthcare by enabling personalized interventions that integrate multimodal data to support rehabilitation, preventive care, and remote monitoring. Despite their broad potential, older adults remain underrepresented in model development, raising concerns ...
Tue T. Te +3 more
wiley +1 more source
Geriatric Total Hip Arthroplasty: Fixation Strategies, Approaches and Outcomes. [PDF]
Saber B, Agrawal DK.
europepmc +1 more source
ABSTRACT Aim This study aimed to investigate the incidence and characteristics of nursing‐sensitive adverse events (NSAEs) in older adults (≥ 65 years) hospitalised with traumatic injuries, and to explore associations with frailty, demographic factors, injury characteristics and hospital‐related factors.
Hanna Järbrink +4 more
wiley +1 more source
Contraindications of femoral implants in primary total hip arthroplasty : legal implications and strategies for orthopaedic surgeons. [PDF]
Manzo MA +3 more
europepmc +1 more source

