Results 241 to 250 of about 83,987 (311)

A Systematic Review on Disease‐Modifying Therapies in Parkinsonian Disorders

Clinical Pharmacology &Therapeutics, EarlyView.
Parkinsonian disorders, including Parkinson's disease, Lewy body dementia, multiple system atrophy, and progressive supranuclear palsy, are progressive neurodegenerative conditions with no treatment options to slow disease progression. This systematic review provides an overview of evidence of disease‐modifying therapies that have been evaluated in ...
Pepijn P.N.M. Eijsvogel, Lars M.G. Smits, Philip H.C. Kremer, Geert Jan Groeneveld   +3 more
wiley   +1 more source

Day-Case Total Hip Replacement for a Neck of Femur Fracture. [PDF]

Cureus
Singh A, Rajgor HD, Moores T, Salim M.
europepmc   +1 more source

Zebrafish inversin mutants develop scoliosis in the absence of laterality defects

Developmental Dynamics, EarlyView.
Abstract Background Human mutations in INVERSIN are associated with nephronophthisis, variable penetrance of situs inversus and congenital heart disease. Inversin has been shown to localize to cilia and many of the patient phenotypes are attributed to disrupted cilia function.
Christopher J. Derrick, Lorraine Eley, Deborah J. Henderson, Bill Chaudhry   +3 more
wiley   +1 more source

Social inequalities in patient outcomes after total hip replacement surgery for osteoarthritis in England: A population-based cohort study of the National Joint Registry. [PDF]

PLoS Med
Patel R, Lenguerrand E, Ben-Shlomo Y, French J, Rangan A, Brittain R, Deere K, Sayers A, Blom AW, Whitehouse MR, Judge A.   +10 more
europepmc   +1 more source

Ecological Momentary Interventions in the Management of Eating Disorders and Obesity: A Systematic Review

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This systematic review evaluated the feasibility, efficacy, adherence, and methodological quality of ecological momentary intervention (EMI)–based treatments for individuals with diagnosed eating disorders (EDs) and/or obesity. Method Eight electronic databases were systematically searched from inception to January 2026.
Wenlu Mao, Ricarda Schmidt, Emily K. Presseller, Adrienne Juarascio, Anja Hilbert   +4 more
wiley   +1 more source

Management of Acetabular Fractures with Total Hip Replacement: A Narrative Literature Review. [PDF]

J Pers Med
Tigani D, Lamattina L, Assenza A, Melucci G, Pizzo A, Donadono C.   +5 more
europepmc   +1 more source

NMDAR‐antibody encephalitis: Seizure semiology and EEG findings

Epileptic Disorders, EarlyView.
Abstract Background N‐methyl‐D‐aspartate receptor antibody encephalitis (NMDAR‐Ab‐E) is an autoantibody‐mediated disorder, characterized by acute development of neuropsychiatric symptoms, seizures, movement disorders, and autonomic instability. Objectives To describe acute seizure semiology and electroencephalogram (EEG) findings in patients with a ...
Maria Emilia C. Andraus, Bernard Liem, Sidra Aurangzeb, Mkael Symmonds, Adam E. Handel, Sarosh R. Irani, Arjune Sen   +6 more
wiley   +1 more source

Comparative Analysis of Hip Abductor Strength Following Anterolateral Versus Posterior Approaches in Total Hip Replacement: A Prospective Study. [PDF]

Cureus
Kumar M, Agarwal D, Sharma A.
europepmc   +1 more source

An n‐of‐1 gene‐directed drug repurposing trial for an ultrarare genetic condition

Epilepsia, EarlyView.
Abstract Objective Gain‐of‐function (GoF) variants in the KCNC1 potassium channel subunit gene (Kv3.1) cause motor/cognitive delays and hypotonia and have been associated with seizures. Fluoxetine has inhibitory effects on Kv3.1. However, open‐label nonrandomized administration is insufficient to guide clinical decision‐making in ultrarare conditions ...
Vedika Jha, Christina Tsetsos, Mark Bedford, Gregory Costain, Sunita Vohra, Juan Pablo Diaz Martinez, Elise Heon, Jacob Vorstman, Carolina Gorodetsky, Ajoy Vincent, Jesiqua Rapley, Lori Anderson, Evdokia Anagnostou, Danielle A. Baribeau   +13 more
wiley   +1 more source

Identifying Risk Groups in 73,000 Patients with Diabetes Receiving Total Hip Replacement: A Machine Learning Clustering Analysis. [PDF]

J Pers Med
Ahmadi A, Kaywood AJ, Chavarria A, Omobhude OF, Kiss A, Faltyn M, Hoellwarth JS.   +6 more
europepmc   +1 more source