Results 61 to 70 of about 160,700 (274)

Translating Muscle RNAseq Into the Clinic for the Diagnosis of Muscle Diseases

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Approximately half of patients with hereditary myopathies remain without a definitive genetic diagnosis after DNA next‐generation sequencing (NGS). Here, we implemented transcriptome analysis of muscle biopsies as a complementary diagnostic tool for patients with muscle disease but no definitive genetic diagnosis after exome ...
Alba Segarra‐Casas, Cristina Domínguez‐González, Daniel Natera‐de Benito, Solange Kapetanovic, Aurelio Hernández‐Laín, Berta Estévez‐Arias, Laura Llansó, Carlos Ortez, Cristina Jou, Itxaso Martí‐Carrera, Arístides López‐Márquez, Maria José Rodríguez, Laura González‐Mera, Velina Nedkova, Roberto Fernández‐Torrón, Benjamín Rodríguez‐Santiago, Cecília Jimenez‐Mallebrera, Raul Juntas‐Morales, Adolfo López‐de Munain, Jordi Surrallés, Andrés Nascimento, Eduard Gallardo, Montse Olivé, Pia Gallano, Lidia González‐Quereda   +24 more
wiley   +1 more source

Superiorized method for metal artifact reduction [PDF]

, 2020
Metal artifact reduction (MAR) is a challenging problem in computed tomography (CT) imaging. A popular class of MAR methods replace sinogram measurements that are corrupted by metal with artificial data. While these ``projection completion'' approaches are successful in eliminating severe artifacts, secondary artifacts may be introduced by the ...
arxiv   +1 more source

My total hip replacement [PDF]

British Journal of Sports Medicine, 2020
My mother had a total hip replacement (THR) 20 years ago, at age 50, just after my dad had died of a brain tumour. She would say, ‘at least this hip problem is not life threatening’. After mum’s joint replacement surgery, I saw her live life to the full—including jet-skiing, tandem paragliding!
openaire   +2 more sources

Patient Perceptions of Medication Therapy for Prevention of Posttraumatic Osteoarthritis Following Anterior Cruciate Ligament Injury: A Qualitative Content Analysis

Arthritis Care &Research, EarlyView.
Objective Posttraumatic osteoarthritis (PTOA) accounts for nearly 12% of osteoarthritis incidences and often occurs after anterior cruciate ligament (ACL) tear. Ensuring the uptake of preventive treatments for PTOA requires that investigators and clinicians understand factors influencing patients to seek preventive therapies.
Lily M. Waddell, Donald P. Mitchener, Kelly C. Frier, Morgan H. Jones, Elena Losina, Nick Bansback, Liana Fraenkel, Jason S. Kim, Jeffrey N. Katz, Faith Selzer, Adam Easterbrook   +10 more
wiley   +1 more source

Are changes in radiological leg alignment and femoral parameters after total hip replacement responsible for joint loading during gait?

BMC Musculoskeletal Disorders, 2019
Background Gait kinematics after total hip replacement only partly explain the differences in the joint moments in the frontal plane between hip osteoarthritis patients after hip replacement and healthy controls.
Stefan van Drongelen, Hanna Kaldowski, Timur Tarhan, Ayman Assi, Andrea Meurer, Felix Stief   +5 more
doaj   +1 more source

Total hip replacement and NICE [PDF]

BMJ, 2005
New guidelines need to address several areas of uncertainty A round 150-200 different hip prostheses are available for use. Some require cement fixation, some are cementless, and each consists of an acetabular and a femoral component. The evolution of hip replacement led to alterations in design and materials, some of which proved disastrous (the 3M ...
Matthew R Utting, R.F. Spencer, B J A Lankester, L K Smith   +3 more
openaire   +3 more sources

Two‐Year Follow‐Up of a Multidisciplinary Lifestyle Intervention for Rheumatoid Arthritis and Osteoarthritis

Arthritis Care &Research, Accepted Article.
Objective The Plants for Joints intervention (PFJ), including a whole‐food plant‐based diet, exercise, and stress reduction, reduced signs and symptoms of rheumatoid arthritis (RA) or metabolic syndrome‐associated hip or knee osteoarthritis (MSOA) compared to usual care. This study examined outcomes two years later. Methods After two 16‐week randomized
Carlijn A. Wagenaar, Wendy Walrabenstein, Marike van der Leeden, Franktien Turkstra, Martijn Gerritsen, Jos W.R. Twisk, Maarten Boers, Martin van der Esch, Henriët van Middendorp, Peter J.M. Weijs, Dirkjan van Schaardenburg   +10 more
wiley   +1 more source

The remarkable solar twin HIP 56948: a prime target in the quest for other Earths [PDF]

, 2012
We study HIP 56948, the best solar twin known to date, to determine with an unparalleled precision how similar is to the Sun in its physical properties, chemical composition and planet architecture. We explore whether the abundances anomalies may be due to pollution from stellar ejecta or to terrestrial planet formation.
arxiv   +1 more source

Moderators and mediators of pain and function outcomes in a new service delivery model for management of knee osteoarthritis in primary care (PARTNER): Secondary exploratory analysis of a randomized controlled trial

Arthritis Care &Research, Accepted Article.
Objective Explore moderators and mediators influenced changes in pain and function in people with knee osteoarthritis (OA) receiving a new model of primary care service delivery (PARTNER), at 12 months (ACTRN12617001595303). Methods Secondary analyses of a cluster randomized controlled trial comparing PARTNER to usual general practitioner‐delivered ...
Abdolhay Farivar, Jocelyn L Bowden, Kim L Bennell, Andrew M Briggs, Stephen J Bunker, Rana S Hinman, Thorlene Egerton, Simon D French, Marie Pirotta, Karen Schuck, Venkatesha Venkatesha, Nicholas A Zwar, David J Hunter   +12 more
wiley   +1 more source

Black hip: a rare case treated by total hip replacement

Annals of Saudi Medicine, 2013
BACKGROUND AND OBJECTIVE: Ochronic arthropathy of hip (Black Hip) is a rare clinical manifestation of congenital disorder of amino acid metabolism characterized by a classic triad: (1) degenerative arthritis, (2) ochronotic pigmentation, and (3) urine ...
Narayana Gowda, Mohan J. Kumar, Ajith K. Kumar   +2 more
doaj   +1 more source