Results 141 to 150 of about 81,866 (353)

Reduced opioids after total joint replacement surgery (REPAIRS): a pilot randomized controlled trial

open access: yesJournal of Orthopaedic Surgery and Research
Background Opioid analgesics are commonly used for controlling pain after total knee or hip replacement. However, it is unclear how much opioid should be prescribed at discharge after total hip and knee replacement surgery to optimize pain management but
Zhiwei Yang   +1 more
doaj   +1 more source

Targeting Golgi–STING Signaling to Reprogram Innate and Adaptive Immunity for the Treatment of Implant‐Associated Infections

open access: yesAdvanced Science, EarlyView.
This study presents an ultrasound‐responsive nanoplatform, CS‐BT@MZ@NEs, with a BaTiO3/Mn‐Zif‐8 core and a chondroitin sulfate coating for Golgi targeting. By leveraging neutrophil hitchhiking, it enables targeted delivery to infection sites. Under ultrasound stimulation, CS‐BT@MZ@NEs generates ROS and modulates Golgi pH to activate cGAS–STING ...
Shicheng Huo   +7 more
wiley   +1 more source

Biomechanical characterisation of leg movement during the golf swing following knee surgery

open access: yes, 2012
The forces transmitted through the knee throughout the golf swing have been found to be as high as those associated with running (Colwell et al., 2005) therefore playing golf with a knee that has undergone surgery may place extra stress on the previously
Murray, P   +17 more
core  

Achieving important improvement in womac pain and function by three months post-surgery influences satisfaction 1 year following total knee replacement [PDF]

open access: bronze, 2018
Aileen M. Davis   +10 more
openalex   +1 more source

Mastication‐Induced Electrical Stimulation Activates Prg4+ Chondroprogenitors for Osteoarthritis Therapy

open access: yesAdvanced Science, EarlyView.
This study presents a ″trash‐to‐treasure″ strategy that converts harmful joint overloads into beneficial electrical cues. The biodegradable MagPie, by providing piezoelectrical stimulation and releasing Mg2+ during mastication, exerts synergistic pro‐regenerative and anti‐inflammatory effects on Prg4+ cells via the ECM‐mediated FAK‐PI3K‐Akt axis ...
Shi‐Yang Feng   +10 more
wiley   +1 more source

Four Station Knee Simulator Wear Testing Comparing Titanium Niobium Nitride with Cobalt Chrome

open access: yes, 2013
A new non-destructive method was applied in order to assess bone integrity. The method is based on measurement of bHypersensitivity to an orthopaedic implant was first published in 1966 and since then, in sensitive patients, is known to cause serious ...
Blunn GW, MRM
core  

History of Total Knee Replacement [PDF]

open access: yes, 2010
Hinge arthroplasty was first introduced over 100 years ago, and it has been refined over the years through a succession of increasingly complex designs that have led to the present rotating hinge prosthesis.
양익환
core  

Comparison of gait kinetics in total and unicondylar knee replacement surgery [PDF]

open access: green, 2018
Stephen D. Miller   +6 more
openalex   +1 more source

Lesion Site‐Targeted Microspheres Modulate Nav1.7‐Related Signaling for Osteoarthritis Treatment

open access: yesAdvanced Science, EarlyView.
Cartilage‐targeted carbamazepine‐loaded WYRGRL‐modified composite microspheres (CBZ/WCOM) anchor to exposed type II collagen in osteoarthritic lesions and release carbamazepine under acidic conditions. This bind‐then‐release platform modulates Nav1.7‐related sodium signaling, Na⁺/Ca²⁺ exchanger‐associated Ca2+ dynamics, and heat shock protein 70 ...
Cheng Chen   +15 more
wiley   +1 more source

Micro‐Galvanic Coupling Programs the Therapeutic Zinc Ion Window to Reconfigure Immune Cascades for Pro‐Regenerative Bone Healing

open access: yesAdvanced Science, EarlyView.
This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun   +14 more
wiley   +1 more source

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