Results 81 to 90 of about 61,800 (289)

Algorithms and statistical analysis for linear structured weighted total least squares problem

Geodesy and Geodynamics
Weighted total least squares (WTLS) have been regarded as the standard tool for the errors-in-variables (EIV) model in which all the elements in the observation vector and the coefficient matrix are contaminated with random errors.
Jian Xie, Tianwei Qiu, Cui Zhou, Dongfang Lin, Sichun Long   +4 more
doaj   +1 more source

CD20+FCRL4+ B Cells Activate CD8+ T Cells via MHC‐I Restriction in Nasopharyngeal Carcinoma Anti‐Tumor Immunity

Advanced Science, EarlyView.
CD20⁺FCRL4⁺ B cells in nasopharyngeal carcinoma actively cross‐present exogenous tumor antigens via MHC‐I, enhancing CD8⁺ T‐cell activation, memory formation, and cytotoxicity. IFNγ‐driven WDFY4 upregulation facilitates this process. These findings reveal an unconventional B‐cell–mediated antitumor mechanism and indicate potential relevance to ...
Benjian Zhang, Xiaotian Yuan, Kelei Gao, Bo You, Yaxuan Wang, Lai Meng, Zirong Chen, Shaobing Xie, Yunqing Liu, Zijian Dong, Shumin Xie, Ruohao Fan, Fengjun Wang, Junyi Zhang, Zhihai Xie, Yongzhen Mo, Hua Zhang, Weihong Jiang   +17 more
wiley   +1 more source

Meta‐GWAS of Pig Semen Quality Traits Reveals Conserved Genes Regulating Mammalian Fertility

Advanced Science, EarlyView.
This study incorporated 14 210 individuals to perform a GWAS meta‐analysis of six semen quality traits. The GWAS meta‐analysis identifies 234 GWAS loci associated with semen quality traits. The incorporation with a functional genomics resource explains potential genetic regulation of ∼40% GWAS signals underlying semen quality traits.
Qing Lin, Xiaodian Cai, Zhanming Zhong, Tingting Li, Xinyou Chen, Wondossen Ayalew, Zhiting Xu, Chen Wei, Xiaoke Zhang, Hong Cheng, Zhenyang Zhang, Xuehua Li, Yongjie Tang, Siqian Chen, Jun Zhou, Jinglei Si, Xibo Wu, Chao Ning, Qishan Wang, Yuchun Pan, Yahui Gao, Jiaqi Li, Ying Yu, Zhe Zhang, Yunxiang Zhao, Lingzhao Fang, Zhe Zhang   +26 more
wiley   +1 more source

GAN‐LSTM‐3D: An efficient method for lung tumour 3D reconstruction enhanced by attention‐based LSTM

CAAI Transactions on Intelligence Technology, EarlyView., 2023
Abstract Three‐dimensional (3D) image reconstruction of tumours can visualise their structures with precision and high resolution. In this article, GAN‐LSTM‐3D method is proposed for 3D reconstruction of lung cancer tumours from 2D CT images. Our method consists of three phases: lung segmentation, tumour segmentation, and tumour 3D reconstruction. Lung
Lu Hong, Mohammad Hossein Modirrousta, Mohammad Hossein Nasirpour, Mohammadreza Mirshekari Chargari, Fardin Mohammadi, Seyed Vahid Moravvej, Leila Rezvanishad, Mohammadreza Rezvanishad, Ivan Bakhshayeshi, Roohallah Alizadehsani, Imran Razzak, Hamid Alinejad‐Rokny, Saeid Nahavandi   +12 more
wiley   +1 more source

Götterdämmerung over total least squares

Journal of Geodetic Science, 2016
The traditional way of solving non-linear least squares (LS) problems in Geodesy includes a linearization of the functional model and iterative solution of a nonlinear equation system.
Malissiovas G., Neitzel F., Petrovic S.
doaj   +1 more source

A Versatile Three Dimensional Traction Force Microscopy Framework for Uncovering the Mechanics of Bio‐Adhesion

Advanced Science, EarlyView.
This study introduces a versatile platform for quantifying three dimensional traction forces at bio‐adhesive interfaces. Integrating in situ stereo‐digital image correlation with finite element simulations allows for precise measurement of microscale displacements and traction forces in both dry and wet conditions.
Yingwei Hou, Fusheng Wang, Tao Liu
wiley   +1 more source

The Microbiota Shapes Central Nervous System Myelination in Early Life

Advanced Science, EarlyView.
Gut microbiota shapes brain development by regulating myelination and glial cell maturation in early life. Using germ‐free (GF) mice and zebrafish, this study reveals sex‐ and age‐dependent effects on myelin growth, integrity, and related gene expression.
Caoimhe M. K. Lynch, Emily G. Knox, Daniel Soong, Thomaz F. S. Bastiaanssen, Kalevi Trontti, Gabriel S. S. Tofani, Sophia Ivaschuk, Michael K. Collins, Donia Arafa, Jatin Nagpal, Iiris Hovatta, David A. Lyons, Gerard Clarke, John F. Cryan   +13 more
wiley   +1 more source

Spatially Resolved Multiomics Reveals Metabolic Remodeling and Autophagy Activation in Adamantinomatous Craniopharyngiomas

Advanced Science, EarlyView.
Multiomics integration analysis reveals the “cystic fluid–tumor cell” metabolic coupling that mediates active choline/ethanolamine uptake of tumor cells from cystic fluid and PC/PE synthesis pathways reprogramming that mediating autophagy pathway activation within ACP. ABSTRACT Adamantinomatous craniopharyngioma (ACP), a benign yet highly recurrent and
Dongting Chen, Yahui Gao, Yulin Wang, Ting Lei, Zheng Qu, Yuhan An, Jiaxu Fu, Xin Li, Fangjun Liu, Yan Li   +9 more
wiley   +1 more source

On The Errors-In-Variables Model With Singular Dispersion Matrices

Journal of Geodetic Science, 2014
While the Errors-In-Variables (EIV) Model has been treated as a special case of the nonlinear Gauss- Helmert Model (GHM) for more than a century, it was only in 1980 that Golub and Van Loan showed how the Total Least-Squares (TLS) solution can be ...
Schaffrin B., Snow K., Neitzel F.
doaj   +1 more source

A glassy contribution to the heat capacity of hcp $^4$He solids

, 2010
We model the low-temperature specific heat of solid $^4$He in the hexagonal closed packed structure by invoking two-level tunneling states in addition to the usual phonon contribution of a Debye crystal for temperatures far below the Debye temperature ...
A. Driessen, A. Penzev, A. Penzev, A.C. Clark, A.C. Clark, A.F. Andreev, A.J. Leggett, A.S.C. Rittner, A.S.C. Rittner, A.V. Balatsky, Alexander V. Balatsky, B. Hunt, C.A. Burns, C.A. Burns, D.A. Ackerman, D.S. Greywall, D.S. Greywall, D.S. Greywall, E. Blackburn, E. Kim, E. Kim, E. Kim, E.C. Helmets, E.O. Edwards, G. Bonfait, G.V. Chester, I.A. Todoshchenko, I.A. Todoshchenko, J. Day, J. Day, J. Day, J. Day, J. Jäckle, J. Zimmermann, J.C. Lasjaunias, J.C. Lasjaunias, J.M. Goodkind, J.P. Frank, J.T. West, Jung-Jung Su, L. Reatto, M. Kondo, M.A. Paalanen, M.J. Graf, M.J. Graf, M.W. Ray, M.W. Ray, Matthias J. Graf, P.W. Anderson, P.W. Anderson, S. Balibar, S. Sasaki, V.N. Grigor’ev, V.N. Grigor’ev, W.A. Phillips, X. Lin, X. Lin, X. Lin, Y. Aoki, Y. Aoki, Z. Nussinov   +60 more
core   +1 more source