Results 11 to 20 of about 16,267 (112)

Partial Inhibition of the 6-Phosphofructo-2-Kinase/Fructose-2,6-Bisphosphatase-3 (PFKFB3) Enzyme in Myeloid Cells Does Not Affect Atherosclerosis

Frontiers in Cell and Developmental Biology, 2021
BackgroundThe protein 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase-3 (PFKFB3) is a key stimulator of glycolytic flux. Systemic, partial PFKFB3 inhibition previously decreased total plaque burden and increased plaque stability.
Renée J. H. A. Tillie, Jenny De Bruijn, Javier Perales-Patón, Javier Perales-Patón, Lieve Temmerman, Yanal Ghosheh, Kim Van Kuijk, Marion J. Gijbels, Marion J. Gijbels, Marion J. Gijbels, Peter Carmeliet, Peter Carmeliet, Peter Carmeliet, Klaus Ley, Klaus Ley, Julio Saez-Rodriguez, Julio Saez-Rodriguez, Judith C. Sluimer, Judith C. Sluimer   +18 more
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The added values of 18F-FDG PET/CT in differentiating cancer recurrence and osteoradionecrosis of mandible in patients with treated oral squamous cell carcinoma

EJNMMI Research, 2023
Background Osteoradionecrosis (ORN) of the jaw requires a differential diagnosis to exclude cancer recurrence. Here, we sought to develop a scoring system comprising 18F-FDG PET/CT parameters for distinguishing between the two conditions in patients with
Nai-Ming Cheng, Chien-Yu Lin, Chun-Ta Liao, Din-Li Tsan, Shu-Hang Ng, Tzu-Chen Yen   +5 more
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The value of PET/CT for the diagnosis and evaluation of immunotherapy in occult primary renal cell carcinoma: a case report

Journal of International Medical Research, 2023
Skin and soft tissue diffusion metastasis (also known as occult cancer) is rare in renal cell carcinoma (RCC). Here, we report an extremely rare case of a 67-year-old male patient with occult primary RCC who developed metastases to the gums, skin, and ...
Ting Jiang, Hongjuan Zheng, Ke Dong, Wen Guanghua, Shishi Zhou, Chenghui Li, Mengjie Dong, Jianfei Fu   +7 more
doaj   +1 more source

Assessment of mediastinal tumors using SUVmax and volumetric parameters on FDG PET/CT [PDF]

Asia Oceania Journal of Nuclear Medicine and Biology, 2017
Objective(s): This study aimed to evaluate the role of pretreatment SUVmax and volumetric FDG positron emission tomography (PET) parameters in the differentiation between benign and malignant mediastinal tumors.
Takahiro Morita, Mitsuaki Tatsumi, Mana Ishibashi, Kayako Isohashi, Hiroki Kato, Osamu Honda, Eku Shimosegawa, Noriyuki Tomiyama, Jun Hatazawa   +8 more
doaj   +1 more source

[18F]FDG PET/CT predicts progression-free survival in patients with idiopathic pulmonary fibrosis

Respiratory Research, 2017
Background Idiopathic pulmonary fibrosis (IPF) is a devastating disease characterized by an unpredictable course. Prognostic markers and disease activity markers are needed.
Aurélien Justet, Astrid Laurent-Bellue, Gabriel Thabut, Arnaud Dieudonné, Marie-Pierre Debray, Raphael Borie, Michel Aubier, Rachida Lebtahi, Bruno Crestani   +8 more
doaj   +1 more source

Can positron emission tomography–computed tomography-based three target lesions' total lesion glycolysis predict therapeutic response in Hodgkin Lymphoma?

The Egyptian Journal of Radiology and Nuclear Medicine, 2022
Background Universally maximum standardized uptake value (SUVmax) and lactate dehydrogenase (LDH) are used as tools for response assessment in Hodgkin Lymphoma (HL) patients. Our objectives are to evaluate the predictive potential and response assessment
Hend Yehia Ali, Shaimaa Abdelsattar Mohammad, Ali Hagag Ali, Ahmed Mohamed Monib, Mennatallah Hatem Shalaby   +4 more
doaj   +1 more source

Pretreatment Metabolic Tumor Volume of Primary Tumor and Total Lesion Glycolysis of Lymph Nodes are Predictive in Nasopharyngeal Cancer

Erciyes Medical Journal, 2020
Objective: Conventional prognostic factors are not yet sufficient to predict treatment outcomes factors in nasopharyngeal carcinoma (NPC). Parameters from PET/CT are still being investigated as a prognostic factor in nasopharyngeal cancer.
Mete Gündoğ, Ummuhan Abdulrezzak
doaj   +1 more source

Prognostic value of F-FDG PET/CT metabolic parameters in small cell lung cancer

Journal of International Medical Research, 2020
Objective To compare the prognostic values of metabolic parameters from pretreatment PET/CT between limited disease (LD) and extensive disease (ED) small cell lung cancer (SCLC) patients. Methods Data on 118 newly diagnosed SCLC patients (50 LD and 68 ED)
Eun Kyoung Choi, Minjae Park, Jooyeon Jamie Im, Yong-An Chung, Jin Kyoung Oh   +4 more
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PET-Based Volumetric Biomarkers for Risk Stratification of Non-Small Cell Lung Cancer Patients

Diagnostics, 2021
Despite the recent advances in lung cancer biology, molecular pathology, and treatment, this malignancy remains the leading cause of cancer-related death worldwide and non-small cell lung cancer (NSCLC) is the most common form found at diagnosis ...
Sara Pellegrino, Rosa Fonti, Alessandro Pulcrano, Silvana Del Vecchio   +3 more
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The Relationship Between KRAS Mutation and 18F-FDG Uptake Parameters in Colorectal Cancer

Bagcilar Medical Bulletin, 2022
Objective:Our purpose in this study was to evaluate whether Kirsten rat sarcoma viral oncogene (KRAS) exon-2 mutation affected 18F-fluorodeoxyglucose (FDG) accumulation patterns, total lesion glycolysis and metabolic tumor volume in colorectal cancer ...
Aynur Özen, Serkan Menekşe, Esat Namal, Aslı Kahraman Akkalp, Merve Tokoçin, Talar Vartanoğlu, Emel Gökmen, Fatih Çelebi   +7 more
doaj   +1 more source