Results 221 to 230 of about 6,772,023 (299)

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

open access: yesAdvanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu   +16 more
wiley   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

open access: yesAdvanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang   +7 more
wiley   +1 more source

Voltage‐Driven Non‐Volatile Interconversion Between Giant Single‐Domain and Multidomain Magnetic States in a Multiferroic Heterostructure

open access: yesAdvanced Science, EarlyView.
Non‐volatile voltage control of magnetic configurations is achieved in a strain‐coupled multiferroic heterostructure. Voltage pulses reversibly interconvert giant single‐domain and multidomain magnetic states, which remain stable at zero applied voltage. ABSTRACT Voltage control of magnetic states in multiferroic heterostructures represents a promising
M. Ghidini   +11 more
wiley   +1 more source

Self‐Assembly of Organic–Inorganic Copolymers Toward Bio‐Inspired Cementitious Composites

open access: yesAdvanced Science, EarlyView.
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Zonglin Xie   +8 more
wiley   +1 more source

Dysregulation of the MACF1‐Rab14/KIF16B‐FGFR Vesicular Trafficking Axis Skews MSC Lineage Commitment in Glucocorticoid‐Induced Osteoporosis

open access: yesAdvanced Science, EarlyView.
Under normal conditions, MACF1 interacts with Rab14 and facilitates KIF16B‐mediated FGFR vesicle trafficking along microtubules to the plasma membrane, thereby supporting BMSC differentiation. In contrast, chronic GC exposure suppresses MACF1 expression, disrupting this transport and causing intracellular FGFR retention, which blunts osteogenic ...
Peihong Su   +14 more
wiley   +1 more source

Regulating Cells Fate and Function to Facilitate Bone Regeneration via Designing Programmable Bio‐Interactive Materials

open access: yesAdvanced Science, EarlyView.
This article aims to elucidate the biological mechanisms of bone repair and the evolution of material design, highlighting key cellular and molecular processes. It further proposes strategies and prospects for programmable bio‐interactive materials, which enable precisely guided bone tissue regeneration by dynamically regulating cell behavior and the ...
Qingrui Fan   +6 more
wiley   +1 more source

Anomalous Enhancement in MXene‐Based Electrochemical Actuators: Pseudo‐Capacitance‐Induced Multi‐Charge Accumulation in Confined Space

open access: yesAdvanced Science, EarlyView.
We elucidate the electrochemical actuation mechanism of 2D material‐based electrodes within a MXene‐centered framework, linking atomic‐scale surface chemistry to macroscopic performance (see schematic). Mechanistically, the reduction of Ti─O─Ti sites in H2SO4 triggers the accumulation of hydrated ions at confined active sites, resulting in anomalous ...
Jiang Xu   +6 more
wiley   +1 more source

Single‐Cell Profiling Reveals a Protective WNT5A‐ATF3‐FOSB Signaling Axis in Hair Follicle Stem Cells During Androgenetic Alopecia

open access: yesAdvanced Science, EarlyView.
Androgenetic alopecia (AGA) is a common form of hair loss with limited treatment options. Silencing of WNT5A signaling, which is widely known as the trigger of the ncWNT signaling pathway, happens in hair follicle stem cells from balding areas. It leads to downregulation of ATF3 and its target FOSB.
Ruiyu Luo   +10 more
wiley   +1 more source

Synergistic NiO‐NiCo Heterostructure Electrode for Highly Active and Durable Hydrogen Evolution in Industrial Alkaline Water Electrolysis

open access: yesAdvanced Science, EarlyView.
This study presents a NiO–NiCo heterostructure electrode that enhances water dissociation and hydrogen adsorption through synergistic interfacial interactions, verified by electrochemical and spectroscopic analyses. Its high performance in a large‐area single‐cell system under dynamic conditions demonstrates how rational non‐precious catalyst design ...
Jinwoo Lee   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy