Results 41 to 50 of about 6,629,384 (218)

The impact of the introduction of total mesorectal excision on local recurrence rate and survival in rectal cancer : long-term results [PDF]

open access: yes, 2011
To investigate the influence of the introduction of total mesorectal excision (TME) on local recurrence rate and survival in patients with rectal ...
Käser, S. A.   +15 more
core   +2 more sources

Progress on the application of transanal total mesorectal excision in low rectal cancer

open access: yes结直肠肛门外科
Transanal total mesorectal excision (taTME) encompasses two surgical approaches: pure taTME and laparoscopic-assisted taTME. These techniques enable the complete excision of the total mesorectal envelope from bottom to top, aided by laparoscopy and ...
Guo Zixian, He Zewei, Zhong Shibiao
doaj   +1 more source

Understanding the Anatomy of the Denonvilliers Fascia: Review Article

open access: yesJournal of Coloproctology, 2021
The postoperative outcome of rectal cancer has been improved after the introduction of the principles of total mesorectal excision (TME). Total mesorectal excision includes resection of the diseased rectum and mesorectum with non-violated mesorectal ...
Mohammed Yousef Alessa
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Technique for laparoscopic autonomic nerve preserving total mesorectal excision

open access: yes, 2006
With the introduction of total mesorectal excision (TME) for treatment of rectal cancer, the prognosis of patients with rectal cancer is improved. With this better prognosis, there is a growing awareness about the quality of life of patients after rectal
Meijerink, WJHJ   +4 more
core   +1 more source

Transanal total mesorectal excision versus anterior total mesorectal excision for rectal cancer: a propensity-score matched, population-based study in Catalonia, Spain

open access: yes, 2021
Background: the clinical value of transanal total mesorectal excision is debated. Objective: to compare short- and medium-term effects of transanal versus anterior total mesorectal excision for rectal cancer.
Lacy Fortuny, Antonio Ma. de   +12 more
core   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

open access: yesAging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho   +4 more
wiley   +1 more source

Low SLC8A1 in Colorectal Cancer Dictates Radiotherapy Resistance Through Calcium‐Dependent ANXA2+sEVs Driving M2 Polarization of TAMs

open access: yesAdvanced Science, EarlyView.
SLC8A1 deficiency in colorectal cancer cells increases intracellular calcium signaling, promoting the secretion of ANXA2‐enriched small extracellular vesicles. These vesicles reprogram tumor‐associated macrophages towards an M2 phenotype, which in turn fosters a tumor microenvironment conducive to radioresistance and is associated with poor patient ...
Yimin Fang   +18 more
wiley   +1 more source

Grading quality of total mesorectal excision specimen by surgeons

open access: yes, 2018
Background: Total mesorectal excision has been gold standard since 1978. But standardization of surgery with quality assurance of total mesorectal excision specimen has been a challenging issue in developing countries.
Dhiresh Kumar Maharjan   +1 more
core   +1 more source

Economic analysis of open versus laparoscopic versus robot-assisted versus transanal total mesorectal excision in rectal cancer patients:A systematic review [PDF]

open access: yes, 2023
Objectives: Minimally invasive total mesorectal excision is increasingly being used as an alternative to open surgery in the treatment of patients with rectal cancer.
Postma, Maarten J.   +13 more
core   +1 more source

Home - About - Disclaimer - Privacy