Results 171 to 180 of about 133,754 (301)

Relationship Between the Product of Pre‐Treatment Neutrophil and Monocyte Counts and Clinical Outcomes in Rectal Cancer With Suspected Lateral Lymph Node Metastasis

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Aim A novel systemic inflammatory response marker, the neutrophil × monocyte value (NM value), has been identified as a negative predictive factor for responses to chemoradiotherapy in rectal cancer. However, the clinical implications of the NM value remain unknown.
Takayoshi Sasaki, Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Soichiro Ishihara   +9 more
wiley   +1 more source

Short-Term cost impact of compliance with clinical practice guidelines for initial sarcoma treatment [PDF]

Background: The impact of compliance to clinical practice guidelines (CPG) on outcomes and/or costs of care has not been completely clarified.Objective: To estimate relationships between medical expenditures and compliance to CPG for initial sarcoma ...
Anne-Valérie Decouvelaere, Antoine Lurkin, Christophe Bergeron, Dominic Cellier, Dominique Ranchère-Vince, François Gilly, Françoise Ducimetière, Guy De Laroche, Isabelle Ray-Coquard, Jean-Yves Blay, Lionel Perrier, Magali Morelle, Mathieu Laramas, Nathalie Havet, Nicola Cautela, Philippe Thiesse, Pierre Biron, Thierry Philip   +17 more
core  

Selecting patients with rectal cancer for total neoadjuvant therapy based on clinical lymph node status: do we dare? [PDF]

Acta Oncol
Slipsager AB, Lauritzen MB, Buskov LK, Poulsen LØ.   +3 more
europepmc   +1 more source

Diagnostic Accuracy of Size‐Based Preoperative CT Assessment for Predicting Lymph Node Metastasis in Colon Cancer: A Systematic Review and Meta‐Analysis

Annals of Gastroenterological Surgery, EarlyView.
Preoperative CT based on lymph node size shows moderate accuracy for detecting nodal metastasis in colon cancer. In this meta‐analysis of 29 studies (5,634 patients), pooled sensitivity and specificity were 0.69 and 0.66. Size‐based CT alone has limited value for clinical decision‐making.
Yuji Takayama, Tomoya Shimizu, Jun Watanabe, Shimpei Ogawa, Yukihide Kanemitsu   +4 more
wiley   +1 more source

Total neoadjuvant therapy for locally advanced rectal cancer: barriers to implementation in real-world practice. [PDF]

J Cancer Res Clin Oncol
Steike DR, Pepper NB, Gravemeyer S, Bremer A, Glasbrenner B, Brüwer M, Pascher A, Domagk D, Biermann L, Lenz P, Eich HT, Reinartz G.   +11 more
europepmc   +1 more source

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

Total Neoadjuvant Therapy Versus Conventional Chemoradiotherapy in Rectal Cancer: Impact on Tumor Regression Grade and the Predictive Value of CEA. [PDF]

Medicina (Kaunas)
Sarafi A, Leventi A, Athitaki K, Stamou K, Papaconstantinou I, Korkolis D.   +5 more
europepmc   +1 more source

Clinical and treatment-related predictors of complete response after total neoadjuvant therapy for rectal cancer in a large multicenter analysis. [PDF]

Clin Transl Radiat Oncol
Wurschi GW, Schneider M, Becker JN, Frerker B, Vorbach SM, Ehret F, Diefenhardt M, Schunn F, von Gruben ME, Büttner M, Hoffmann E, Rühle A, Beier J, Ferdinandus S, Trommer M, Sahin EC, Hlouschek J, Aninditha K, von Ohlen DS, Kaufmann J, Depardon A, Ha HM, Kessler C, Cieslak A, Trommer S, Fabian A, Sonnhoff M, Rißner F, Römer M, Pietschmann K.   +29 more
europepmc   +1 more source

Chromosomal Instability Identifies High‐Risk Patients With Early‐Stage Non‐Small Cell Lung Cancer

Cancer Nexus, EarlyView.
Chromosomal instability, as measured by fraction genome altered (FGA) from routine targeted next‐generation sequencing, identifies a high‐risk subgroup among patients with stage I–III non‐small cell lung cancer and provides prognostic information that is not captured by traditional clinical factors or tumor mutation burden. ABSTRACT Background Patients
Mobina Shrestha, Salina Dahal, Amir Babu, Yogesh Joshi   +3 more
wiley   +1 more source

Mucin quantity on MRI and outcomes following total neoadjuvant therapy in patients with rectal cancer. [PDF]

Eur Radiol
Javed-Tayyab S, Miranda J, Reif de Paula T, Nevin R, Alves Pinto PV, Zheng J, Firat C, El Homsi M, Rodriguez L, Capanu M, Weiser MR, Shia J, Gollub MJ, Horvat N.   +13 more
europepmc   +1 more source