Results 211 to 220 of about 8,910,770 (392)

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Optimal time for collateral channel wiring in retrograde chronic total occlusion percutaneous coronary intervention. [PDF]

Sci Rep
Lee K, Kim TO, Kwon W, Yoon YH, Kwon O, Lee JY, Lee PH, Kang SJ, Kim YH, Lee CW, Lee SW.   +10 more
europepmc   +1 more source

Usefulness of excimer laser atherectomy for balloon uncrossable lesion in chronic total occlusion

, 2015
Daisuke Sueta, Seiji Hokimoto, Takashi Miyazaki, Kenji Sakamoto, Kenichi Tsujita, Eiichiro Yamamoto, Noriaki Tabata, Sunao Kojima, Koichi Kaikita, Hisao Ogawa   +9 more
openalex   +1 more source

Early Detection of Cell Death Using Transmembrane Water Exchange Magnetic Resonance Imaging

Advanced Science, EarlyView.
Cell death is important in both the development and treatment of cancer. In this study, it is demonstrated for the first time that a specific measurement of the transmembrane water exchange rate using magnetic resonance imaging can be used as an early marker of cell death in mammalian cells, in animals and in human patients. Abstract Cell death plays a
Athanasia Kaika, Luca Nagel, Ulrike Höckendorf, Bangwen Xie, Geoffrey J. Topping, Mathias Schillmaier, Irina Beer, Frits H. A. van Heijster, Julian Rauch, Tristan A. Kuder, Sandra Sühnel, Bernd Erber, Christian Lohrmann, Simone Ballke, Thomas Metzler, Katja Steiger, Philipp J. Jost, Natalia P. Ivleva, Philipp Paprottka, Jonathan Nadjiri, Kevin M. Brindle, Wolfgang A. Weber, Franz Schilling   +22 more
wiley   +1 more source

Reply to: 'Persistent high major adverse cardiac outcome of 7% with chronic total occlusion intervention in patients with stable coronary artery disease'. [PDF]

Neth Heart J
Somsen YBO.
europepmc   +1 more source

CARDIOMARKERS EVALUATION AND MYOCARDIAL ASSESSMENT IN PATIENTS WITH RECANALIZATION OF CHRONIC TOTAL OCCLUSIONS USING HIGH DOSE ATORVASTATIN LOADING

, 2018
А. С. Рагозина, И. В. Петренко, И. А. Урванцева, A. I. Gorkov, К. Yu. Nikolaev   +4 more
openalex   +2 more sources

Endovascular Treatment of Chronic Total Occlusion in the Subclavian Artery: A Review of 23 Cases [PDF]

, 2020
Guochen Niu, Ziguang Yan, Bihui Zhang, Min Yang   +3 more
openalex   +1 more source

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

A Very Rare Complication of Chronic Total Occlusion (CTO) Intervention: Tip of Corsair Micro-Catheter Punctured By Guide-Wire

, 2014
Müslüm Şahin, Serdar Demır, Mehmet Vefik Yazıcıoğlu, Mehmet Muhsin Türkmen   +3 more
openalex   +2 more sources

Low YTHDC1 Expression Upregulates FSCN1 to Promote Nuclear F‐Actin Formation and Facilitate Double‐strand DNA Breaks Repair in TMZ‐Resistant Glioblastoma

Advanced Science, EarlyView.
This study revealed that low expression of YTHDC1 in TMZ‐resistant GBM cells leads to increased FSCN1 expression, which is suppressed by m6A modification. FSCN1 activates the CDC42/N‐WASP/Arp2/3 axis in the cell nucleus by recruiting the guanine nucleotide exchange factor (GEF) family member FGD1, thereby promoting F‐actin polymerization in the nucleus.
Minglong Yang, Wanxiang Niu, Yuanfei Wang, Peng Chen, Maolin Mu, Xiaoming Zhang, Ben Xu, Shanshan Hu, Chaoshi Niu, Pengfei Wu   +9 more
wiley   +1 more source