Results 131 to 140 of about 2,153,594 (310)

Total-pressure measurement in pulsating flows

open access: yes, 1973
Pneumatic-type probe was used as comparison instrument with total pressure tubes to determine true average pressure and, thus, to determine if nonlinear averaging effects were significant.
Dudzinski, T. J.   +2 more
core  

Heel Pressure Ulcers: a study of wound healing [PDF]

open access: yes, 2011
Background Heels are a common location for pressure ulcers (PUs); they may be physiologically different to other PU sites and their healing is poorly understood. Aim To summarise the effects of support surfaces and identify prognostic factors in
McGinnis, Elizabeth
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

Experimental investigation of two-phase pressure drop in a microchannel

open access: yes, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
Palm, B   +3 more
core  

Plantar pressures with total contact casting.

open access: yesJournal of rehabilitation research and development, 1996
Total contact casting has been used to aid in the healing of plantar neurotrophic ulcerations. The efficacy of total contact casts in promoting ulcer healing is presumably due to a reduction in the load over high pressure areas with pressure redistribution over the entire surface of the foot.
J J, Wertsch   +5 more
openaire   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Evolution of total pressure in near microjet region

open access: yes, 2013
Large eddy simulations of a high Reynolds number Mach 0.9 jet fitted with 8, uniformly distributed microjets with a pressure ratio of 1.89 have been performed.
Max Rife (490969)
core   +1 more source

Estimating Grazing Pressure from Satellite Time Series Without Reliance on Total Production

open access: yesRemote Sensing
Accurately assessing grazing impacts is essential for sustaining alpine grasslands. Conventional approaches often rely on total forage productivity, an indirect and uncertain proxy for forage availability.
Yan Shi   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

open access: yesMolecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou   +12 more
wiley   +1 more source

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