Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Pengaruh Penerapan Total Productive Maintenance Terhadap Kinerja Perusahaan Farmasi di Jawa Timur
Many companies increase its organizational capability through investing in such programs as Just In Time (JIT) and Total Quality Management (TQM). Thebenefit of these programs, however, seems always limited because of less reliab1e equipment.
Ernaning Widiaswanti
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Redefining Industrial Maintenance Activity in the Modern Organization of Industrial Companies [PDF]
The maintenance activity isn’t a purpose in itself, it’s a necessity of which “the production suffers” and the financial agent “considers too expensive”. It often exists a conflict between the production units and the maintenance department, not only for
Florea PARVU +3 more
core
Entwicklung einer digitalen Lösung für die Umsetzung von Total Productive Maintenance im Lernort Digitale Umformtechnik [PDF]
Diese Bachelorarbeit umfasst die Entwicklung einer digitalen Lösung für die Umsetzung von Total Productive Maintenance im Lernort Digitale Umformtechnik, sowie die Untersuchung von am Markt etablierten Applikationen.
Kullik, Stephen
core
STRATEGI TOTAL PRODUCTIVE MAINTENANCE UNTUKMENINGKATKAN OEE DI INDUSTRI: SYSTEMATIC LITERATUR REVIEW
Masalah kerusakan mesin yang berulang dan rendahnya efisiensi proses produksi masih menjadi tantangan utama dalam industri manufaktur. Untuk mengatasi hal ini, Total Productive Maintenance (TPM) diterapkan sebagai pendekatan strategis untuk meningkatkan ...
Muhammad Fatkhur Rohman, Hery Irwan
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Penerapan Pemeliharaan Produktif Total (Total Productive Maintenance)
Buku Total Productive Maintenance (TPM) ini merupakan panduan praktis bagi pembaca yang ingin mempelajari terkait dengan TPM. Buku ini memberikan penjelasan ringkas yang disertai dengan contoh penerapan terkait dengan delapan pilar TPM.
Muhammad, Rosiawan +1 more
core +2 more sources
Embedding risk in total productive maintenance model
Abstract The importance of this study comes from the vital contribution Total Productive Maintenance (TPM) makes in improving the maintenance and reliability of machine perfor-mance. Although TPM is widely recognized for its effectiveness in addressing various issues such as failures, setup times, and production defects, current ...
Vickram Chundhoo +3 more
openaire +2 more sources

