Results 91 to 100 of about 8,406,914 (282)

Barreras y facilitadores de la implantación del TPM

Intangible Capital, 2013
Objeto: El TPM (Total Productive Maintenance) resulta difícil de implementar. El presente artículo pretende, a través del análisis de la literatura existente, aproximarse a esa dificultad y aportar un análisis que permita avanzar en su conocimiento ...
Juan A. Marin-Garcia, Rafael Mateo Martínez   +1 more
doaj   +1 more source

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

The impact of total productive maintenance on the manufacturing sector. [PDF]

, 2003
Thesis (MBA)-University of Natal, Durban, 2003.Maintenance philosophies have evolved over a period of time. These philosophies have evolved from breakdown maintenance to ReliabilityCentred Maintenance (RCM).
Mabunda, I. S.
core   +1 more source

Total Productive Maintenance and Industry 4.0: A Literature-Based Path Toward a Proposed Standardized Framework

Applied System Innovation
In the context of Industry 4.0, Total Productive Maintenance (TPM) is undergoing a major shift driven by digital technologies such as the IoT, AI, cloud computing, and Cyber–Physical systems. This study explores how these technologies reshape traditional
Zineb Mouhib, Maryam Gallab, Safae Merzouk, Aziz Soulhi, Mario Di Nardo   +4 more
doaj   +1 more source

An analysis for total productive maintenance implementation [PDF]

, 2010
This report constitutes an evaluation of the effectiveness and cost of a maintenance program for a discrete parts manufacturing company. Total Productive Maintenance (TPM) is an integrated life-cycle approach to factory maintenance operations introduced ...
Olafsson, Sveinn V.
core  

Niche‐Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids

Advanced Science, EarlyView.
Compared to E8, mTeSR1 culture downregulated WNT and TGF‑β signaling, and upregulated neural differentiation pathways, enhancing neural priming. Under skin organoid induction conditions, mTeSR1‑cultured hESCs generated organoids with significantly higher neuroepithelial differentiation.
Zhongliang Chen, Liangxia Jiang, Xianbin Wang, Lili Zhong, Rongcan Luo, Min Su, Liangzhao Chu, Peng Luo   +7 more
wiley   +1 more source

TGFBI Maintains Fibrocartilage Homeostasis by Restraining O‐GlcNAcylation to Inactivate and Destabilize ADAMTS16 in Temporomandibular Joint Osteoarthritis

Advanced Science, EarlyView.
TGFBI deficiency elevates O‐GlcNAcylation, promoting the transcriptional activation of ADAMTS16 and OGT‐mediated post‐translational modification of ADAMTS16 at Ser1170. This leads to its stabilization and accumulation, driving chondrocyte metabolic disorders and senescent phenotypes, ultimately resulting in fibrocartilage dysfunction and TMJOA ...
Xin Liu, Xinyue Luo, Jie Zhao, Ziyan Jiang, Jiayi Zhai, Taomin Zhu, Xueke Jia, Xiaohan Ma, Henghua Jiang, Huimin Li, Yaping Feng, Jin Ke, Xing Long   +12 more
wiley   +1 more source

TOTAL PRODUCTIVE MAINTENANCE AS A REQUIREMENT OF WORLD CLASS MANUFACTURING [PDF]

, 1996
Total Productive Maintenance (TPM) is one of the approaches to World Class Manufacturing which is the application of TQM philosophy and tools in the fields of production, quality assurance and maintenance.
Kövesi, János
core  

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Facing Challenges of Implementing Total Productive Management and Lean Tools in Manufacturing Enterprises

Systems
Manufacturing companies are always looking for ways to outperform their competitors. They are constantly trying to improve their efficiency and reduce costs.
Tomislav Slavina, Nedeljko Štefanić
doaj   +1 more source