Results 241 to 250 of about 14,000 (299)

A distinct gene expression mechanism for d‐amino acid utilization in hyperthermophilic archaeon Pyrococcus horikoshii

The FEBS Journal, EarlyView.
The genes PH0137, PH0138, and PH0140 form a cluster in the genome of Pyrococcus horikoshii. The PH0140 gene encodes a transcription factor identified as a d‐amino acid‐responsive regulatory protein (DARP). In feast mode, l‐Ile‐bound DARP binds to the promoter and represses transcription of PH0137 and PH0138. In famine mode, DARP binds to d‐allo‐Ile and
Ryushi Kawakami, Tomoki Kawase, Taira Uehara, Haruhiko Sakuraba, Tomohiko Matsuzawa, Junji Hayashi, Toshihisa Ohshima   +6 more
wiley   +1 more source

Antisense transcription can induce expression memory via stable promoter repression. [PDF]

Genome Biol
Mutzel V, Schwämmle T, Oeverdieck S, Librenjak L, Boesen B, Bothe M, Gjaltema RAF, Dunkel I, Noviello G, Schulz EG.   +9 more
europepmc   +1 more source

Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants

The FEBS Journal, EarlyView.
Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan, Jafar S. Jabbari, Naomi X. L. Ling, Anne M. Kong, Jia Q. Truong, Marnie L. Maddock, Ayeshah A. Rosdah, Christopher G. Langendorf, Lifang Zhang, Jarmon G. Lees, Sebastian Bass‐Stringer, Danise Ann Onda, Alice Pébay, Mirella Dottori, Kim Loh, Jessica K. Holien, Sean Lal, Nadia M. Davidson, Jonathan S. Oakhill, Shiang Y. Lim   +19 more
wiley   +1 more source

Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle. [PDF]

Food Sci Nutr
Li Y, Li X, Sui X, Liu L, Hanif Q, Wang F, Luo L, Bu Y, Xu S, Wang Y, Lei C, Sun F.   +11 more
europepmc   +1 more source

Machine Learning Model for Predicting Postoperative Pain in Cases of Irreversible Pulpitis

International Endodontic Journal, EarlyView.
ABSTRACT Aim Postoperative pain is a frequent clinical concern following endodontic treatment. This study aimed to develop and validate supervised machine learning models to predict the occurrence of postoperative pain in cases of irreversible pulpitis.
Pedro Felipe de Jesus Freitas, Ingrid Luiza Mendonça Cunha, Thalita de Paris Matos, Flares Baratto‐Filho, Bianca Marques de Mattos de Araujo, Manoel Damião Sousa‐Neto, Leandro de Moura Martins, Fernando José Herkrath, Emílio Carlos Sponchiado‐Júnior, Cristiano Miranda de Araujo   +9 more
wiley   +1 more source

Comparative Study on Feeding Physiology, Metabolic Physiology, and Energy Budget of <i>Meretrix meretrix</i>, <i>Mactra veneriformis</i>, and <i>Ruditapes philippinarum</i> in the Tidal Flat Aquaculture Zone. [PDF]

Animals (Basel)
Liu L, Zhu Y, Xin C, Bao J, Wang F, Han S, Hu H, Zhang X, Li L, Jiang M.   +9 more
europepmc   +1 more source

Urinary extracellular vesicle miRNA signature reflects pancreatic islet stress in type 2 diabetes

Journal of Diabetes Investigation, EarlyView.
Urinary ECV miRNAs show a distinct dysregulation signature in T2D with strong diagnostic performance. This signature mirrors molecular changes across pancreatic islets, blood, liver, and adipose tissue, with the strongest concordance in islets, linking it to β‐cell stress. Overall, they represent a non‐invasive, mechanistically informative biomarker of
Md. Zubbair Malik, Mohammed Dashti, Anwar Mohammad, Mohamed Al‐Sayegh, Mohammed Al‐Onaizi, Rasheeba Nizam, Khadija M Dashti, Mohamed Abu‐Farha, Jehad Abubaker, Fahd Al‐Mulla, Hamad Ali   +10 more
wiley   +1 more source

Going wild in banana breeding enables Fusarium-resistant hybrids with improved fruit quality. [PDF]

Nat Commun
Liu X, Fu N, Li J, Xiao TW, Zeng S, Jiang R, Wang XF, Zhang HY, Wei L, Lu LY, Wang ZF, Yan HF, Li LF, Rouard M, Ge XJ, Li WM, Huang HR.   +16 more
europepmc   +1 more source

Measuring the degree of leanness in logistics service providers: Development of a measurement tool. [PDF]

Haan, J.A.C. de, Naus, A.J.A.M., Overboom, M.A.   +2 more
core   +1 more source