Results 71 to 80 of about 3,309,745 (254)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Pituitary enlargement and hypopituitarism in patient with lung cancer treated with immune checkpoint inhibitors: Metastasis or hypophysitis? Role of imaging

open access: yesRadiology Case Reports
Pituitary gland metastasis is an unusual event, and pituitary metastasis from lung adenocarcinoma is extremely rare and associated with poor prognosis. To date, approximately 16 cases have been reported.
Pier Paolo Arcuri, MD   +5 more
doaj   +1 more source

TQM – A Factor for Tourism Competitiveness [PDF]

open access: yesRomanian Economic Journal, 2017
In a more globalized world, with the rise of the importance of tourism in the global economy (its share in GDP) and the growing competition on the market of global tourism, providing quality tourist products represent a desideratum recognized by all the ...
Mihaela Gabriela Belu   +3 more
doaj  

The impacts of total quality management practices in Algerian higher education institutions. [PDF]

open access: yesFront Psychol, 2022
Yahiaoui F   +6 more
europepmc   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

open access: yesFEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

TOTAL PRODUCTIVE MAINTENANCE, A CENTRAL PREOCCUPATION OF THE MANAGERS [PDF]

open access: yesManagement & Marketing, 2013
This present study demonstrates that the role of the mangers in the productive maintenance is currently becoming more important. This assessment is formulated starting from the daily realities regarding the growth of the proportions of productions and ...
Daniela POPESCU   +2 more
doaj  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

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