Results 111 to 120 of about 5,119,437 (284)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
Effects of Innovation, Total Quality Management, and Internationalization on Organizational Performance of Higher Education Institutions. [PDF]
Front Psychol, 2022 Texeira-Quiros J +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Payesh, 2004 Objective(s): To determine requirements for implementation of a total quality management system at Rasoul Akram Hospital. Methods: This cross-sectional study was conducted in 2003.
Delgoshaei B, Maleki M.R, Dehnavieh R
doaj
Assessment of the quality of independent nursing practice in Indonesia based on total quality management indicators. [PDF]
Belitung Nurs J, 2021 Sahputra D, Lumbantobing P, Tuppal CP.
europepmc +1 more source
The relationship between total quality management implementation and leadership in the Saudi higher education: a review and conceptual framework [PDF]
, 2012 The purpose of this paper is to investigate the implementation of total quality management (TQM) at the Saudi Arabian universities and the best leadership practice in order to improve quality and ranking of Saudi Arabian universities.
Al-Karaghouli, W +2 more
core
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Total Quality Management (TQM) in Hungary II [PDF]
, 1990 Since 1987, Hungary has been adopting the concept of total quality management (TQM) to improve its competitive outlook in world markets. The concept originated in studies carried out by Professor S. Shiba at IIASA in 1986-1987.
Jirasek, J., Peceli, B.
core
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source