Results 121 to 130 of about 512,638 (310)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Calcium‐sensing receptor induces the apoptosis of chondrocytes in cooperation with phosphate transporter

FEBS Open Bio, EarlyView.
Excess Ca2+ ions activate the Calcium‐Sensing Receptor (CaSR), which subsequently drives the uptake of excess inorganic phosphate (Pi) via the Pi transporter (Pit−1) in chondrocytes. This mechanism causes a toxic increase in intracellular Pi concentration, ultimately leading to chondrocyte apoptosis and pathological mineralization. Excess extracellular
Sachie Nakatani, Hiroya Ueda, Ayumi Kawata, Yuki Sato, Kotomi Inomata, Hiroshi Mano, Masahiro Wada, Kenji Kobata   +7 more
wiley   +1 more source

Assessment of the physicochemical properties of the sediment from the Gangetic floodplain wetlands of West Bengal, India, with GIS and a statistical approach

Frontiers in Environmental Science
IntroductionBottom sediments play a pivotal role in wetland productivity, and here, eight Gangetic floodplain wetlands of India were studied to assess the sediment physicochemical characteristics and textural analysis.MethodsSediment samples that were ...
Basanta Kumar Das, Ajoy Saha, Archan Kanti Das, Purna Chandra, Kausik Mondal, Tania Kayal, Sangeeta Chakraborty, Shreya Bhattacharya, Bigan Kumar Sahoo, Chayna Jana   +9 more
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source

The role of Lake Dongting in regulating the sediment budget of the Yangtze River [PDF]

Hydrology and Earth System Sciences, 2005
Lake Dongting, the second largest freshwater lake in China and located in the middle reaches of the River Yangtze catchment, was formed at the beginning of the Holocene period by sea level rise and has varied in size with changes in local weather ...
Shi-bao Dai, Shi-bao Dai, Shi-lun Yang, Jun Zhu, Ang Gao, Peng Li   +5 more
doaj  

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Efficiency and hydraulic performance of the micro-pressure filter in front of the pump studied using PPR and NSGA-II

Guan'gai paishui xuebao
【Objective】 Pump often has a filter installed in the front of it to filter sediments and debris. This paper studied its efficiency and performance. 【Method】 The study was based on physical model, with flow rate being 2-8 m3/h, sediment content being 0.5 ...
TAO Hongfei, LI Qi, ZHOU Yang, Mahemujiang ·Aihemaiti, LI Qiao, JIANG Youwei   +5 more
doaj   +1 more source

Modelling sediment and total phosphorus export from a lowland catchment: Comparing sediment routing methods

, 2014
Bank erosion is the main source of suspended sediment (SS) and diffuse total phosphorus (TP) in many lowland catchments. This study compared a physically based sediment routing method (Physical method), which distinguishes between stream bed and bank erosion, with the original sediment routing method (Original method) within the Soil and Water ...
Lu, Shenglan, Kronvang, Brian, Audet, Joachim, Trolle, Dennis, Andersen, Hans Estrup, Thodsen, Hans, van Griensven, Ann   +6 more
openaire   +2 more sources

Down‐regulation of Shh in the hair follicles of mice during chemotherapy‐induced hair loss is mediated by the JAK/STAT1 signaling pathway

FEBS Open Bio, EarlyView.
We found that during chemotherapy‐induced alopecia (CIA), Sonic hedgehog (Shh) expression significantly decreased in hair follicle Shh+ cells, whereas the Janus‐activated kinase/signal transducer and activator of transcription 1 (JAK/STAT1) signaling pathway was markedly activated.
Ruifang Fan, Jingling Huang, Xiang Lin, Tingjiao Lan, Yuli Tang, Ling Sun, Guixuan Zhou   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source