Results 221 to 230 of about 9,395,070 (255)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Predictive Value of Left Atrial Strain Combined with Low-Voltage Substrate for Recurrence After Radiofrequency Catheter Ablation in Persistent Atrial Fibrillation. [PDF]

Diagnostics (Basel)
Ma N, Cui X, Li R, Li Y, Wang Y, Zhang J.   +5 more
europepmc   +1 more source

Sleep and Drowsiness in Cattle: A Narrative Review of Physiology, Measurement, and Methodological Challenges. [PDF]

Animals (Basel)
Torres PHF, Alves FF, Lopes MEM, Virgínio Júnior GF, O'Hara BF, Donohue KD, Watanabe DHM, Millen DD.   +7 more
europepmc   +1 more source

Convergent Hybrid Ablation and Concomitant Left Atrial Appendage Exclusion for Stroke Prevention and Rhythm Control in Persistent Atrial Fibrillation. [PDF]

J Clin Med
Toma YR, Damgaard S, Carranza CL.
europepmc   +1 more source

Epicardial-to-Endocardial Activation Gradients and Conduction Block During Atrial Fibrillation in the Human Left Atrial Posterior Wall. [PDF]

Circ Arrhythm Electrophysiol
Wong CX, Lee XW, Badhwar N, Alvarez CK, Lee AM, Woods CE, Dewland TA, Gerstenfeld EP, Beygui RE, Lee RJ.   +9 more
europepmc   +1 more source

Effects of Structural and Electrical Defects on Vibration Suppression and Energy Harvesting Performance of Piezoelectric Metamaterial Beam. [PDF]

Micromachines (Basel)
Wang H, Jin X, Wang G, Sun X.
europepmc   +1 more source

Expanding the Porous Alumina Engineering Toolbox for Nanooptics: Multiscale Morphological Tuning via Square-Wave Pulse Anodizing. [PDF]

ACS Omega
Pashchanka M.
europepmc   +1 more source