Results 111 to 120 of about 597 (229)

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand   +2 more
wiley   +1 more source

An integrated platform for 2‐D and 3‐D optical and electrical mapping of arrhythmias in Langendorff‐perfused rabbit hearts

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Integrated multimodal platform for panoramic cardiac mapping in isolated heart experiments. On the left, an image of the experimental setup during data acquisition showing a Langendorff‐perfused rabbit heart surrounded by three optical cameras (CAM A, B and C) positioned 120° apart, each coupled with high‐power LEDs for panoramic
Jimena Siles   +8 more
wiley   +1 more source

On the total vertex irregularity strength of firecracker graph

open access: yesJournal of Physics: Conference Series, 2019
A Haryanti, D Indriati, T S Martini
openaire   +1 more source

Utility of local capillary supply indices: Insights from computational image‐based modelling

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Local capillary distribution and fibre geometry influence oxygen availability in skeletal muscle. Image‐based modelling of tissue PO2${{P}_{{{{\mathrm{O}}}_2}}}$ shows that area‐based measures of capillary supply – the local capillary density (LCDi) and local maximum diffusion distance (Dmax,i) – most accurately represent the ...
Abdullah A. Al‐Shammari   +6 more
wiley   +1 more source

Insights from electromechanical simulations to assess omecamtiv mecarbil efficacy in heart failure

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Impact of Omecamtiv Mecarbil (OM) on in‐silico models of heart failure. A mathematical electromechanical model of human ventricular tissue is used to simulate the effects of OM in heart failure with reduced ejection fraction (HFrEF).
Maria Teresa Mora   +8 more
wiley   +1 more source

Enhanced Efficacy of Laser‐Activated Irrigation (Er,Cr:YSGG) in Eradicating Enterococcus faecalis Biofilm in 3D‐Printed Molar Replicas: A Pilot Study

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives This study compared the efficacy of Sonic (EDDY) and Er,Cr:YSGG (2780 nm) laser activation in eradicating Enterococcus faecalis biofilm formed in 3D‐printed molar replicas with two mesial canals and one distal canal. Materials and Methods An in vitro design was implemented using 20 3D‐printed mandibular molar replicas mimicking the ...
Margarida Macedo   +4 more
wiley   +1 more source

The Homeobox Genes: Classification, Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 7, Issue 4, April 2026.
Overview of the homeobox gene superfamily and its pathophysiological roles. The homeobox superfamily comprises several major classes, including ANTP, PRD, TALE, LIM, POU, and others. Among these, the HOX clusters (A–D) play critical roles in embryonic development specifically in conferring cellular identity, regulating morphogenesis, and guiding axial ...
Maedeh Dadzadi   +5 more
wiley   +1 more source

Free‐Breathing Multi‐Slice Co‐Registered Cardiac T1, T2, and ADC Mapping With Spin‐Echo Echo Planar Imaging

open access: yesMagnetic Resonance in Medicine, Volume 95, Issue 4, Page 2035-2051, April 2026.
ABSTRACT Purpose To develop a free‐breathing method for multi‐slice co‐registered cardiac T1, T2, and ADC maps using single‐shot spin‐echo echo planar imaging (SE‐EPI). Methods T1, T2, and diffusion weighted images in five slices were acquired with SE‐EPI readouts during free breathing using interleaved acquisition of slices, non‐selective inversion ...
Dingheng Mai   +16 more
wiley   +1 more source

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