Results 101 to 110 of about 1,974,797 (290)
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
The impact of behaviors and skills of tour guides in guiding tourist groups. [PDF]
African Journal of Hospitality, Tourism and Leisure, 2019 The aim of this study was to reveal the impact of the tour guide's behaviors and skills in guiding tourists groups in an efficient manner. To achieve the aim of the study, a random sample of (117) tour guides were selected and the descriptive approach ...
Dr. Mohammad Shabeb Kassawnh +3 more
doaj
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
The Turtlebot Tour Guide (TTG) [PDF]
, 2019 Applied project submitted to the Department of Computer Science and Information Systems, Ashesi University, in partial fulfillment of Bachelor of Science degree in Management Information Systems, 2019The Turtlebot Tour Guide project is a project that was
Adongo, Ethel
core +1 more source
, 2020 This 4-page guide, from the Minnesota State Advanced Manufacturing Center of Excellence, is a step-by-step outline for hosting a manufacturing community tour. A community tour is "a group of manufacturers in a city or region com[ing] together to
core +1 more source
ELT Worldwide: Journal of English Language TeachingThis research delves into an examination of the language styles employed by tour guides in Huta Siallagan when interacting with international tourists. The primary objectives of this study were twofold: first, to categorize and identify the various types
Sabrina Anjelina Siburian +2 more
doaj +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
, 2023 This tour guide contains information about the COWASEE Basin, made of the Congaree, Santee, and Wateree Rivers, including the history of the region and ...
South Carolina Department of Natural Resources
core +1 more source