Results 91 to 100 of about 596,587 (282)

Irish Girl Guides: health promotion packs

open access: yes, 2003
Irish Girl Guides is delighted to present the HEALTH PROMOTION PACKS. The packs have been designed as.part of our plan to achieve the National Youth Ireland's Q-mark as a Health Promoting Youth Organisation. Health Iriitiative was launched in January
Irish Girl Guides
core  

The ability to speak English of the local tour guides for promoting tourism at the Aceh Tsunami Museum

open access: yesStudies in English Language and Education, 2018
This research aimed to find out the English language proficiency of the local tour guides at the Aceh Tsunami Museum, Aceh, Indonesia, and the difficulties that they faced in communicating with foreign tourists in English.
Sofyan Abdul Gani, Cut Intan Damayanti
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

CHALLENGES IN EDUCATION OF TOUR GUIDES AND TOUR MANAGERS [PDF]

open access: yes, 2012
Članak istražuje različite obrazovne sustave za turističke vodiče u Sloveniji, kao i inozemstvu. Na temelju ankete provedene među vodičima i turističkim pratiteljima u Sloveniji istraživali smo njihovo mišljenje o korisnosti znanja stečena u procesu ...
Gorenak, Mitja, Gorenak, Irena
core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Tour Guides

open access: yes, 1985
Group photo of the SU tour guides. The tour guides play an important role in the admissions process. They discuss student life, both academic and social, as well as other aspects of the University with prospective students and their families during ...
Vannucci Foto-Services
core  

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

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