Results 51 to 60 of about 596,587 (282)

TOUR GUIDE- GUIDE REQUIREMENTS

open access: yes, 2022
This article is devoted to know minor features of the guide profession , personal qualities of the guide, requirements to his skills. And also guide's speech culture, stages of organization of guide activities, minor features of the guide profession.
Rakhimova Charoskhon Odiljonovna   +1 more
openaire   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

A Proposal for an Ethical Code for Tourist Guides in Egypt [PDF]

open access: yesJournal of Tourism, Hotels and Heritage
The tour guide is considered the backbone and nerve of the tourism process, its active element, and one of the most influential people on the tourist's trip.
Zahra Abdel Wahab
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The evaluation on the international tour leader training program in Taiwan, R.O.C. [PDF]

open access: yes, 2000
Plan BThe overall impression of the tour leader for travel business not only affects the travel service’s image, but also customer loyalty. Furthermore, tour leader is the primary factor that differentiates the tour in question from the competitors’ tour.
Lan, Yi-Ping
core  

Identifying and Prioritizing Effective Characteristics on Performance of Incoming Tour Guides from the Perspective of Foreign Tourists Case Study: Incoming Cultural Tour Guides in Tehran [PDF]

open access: yesMuṭāli̒āt-i Mudīriyyat-i Gardishgarī, 2018
Incoming tour guides’ performance as cultural representatives and line workers is very important in cross-cultural interactions. The purpose of this research is to identify and Prioritize effective characteristics on performance of incoming tour guides ...
Mehdi Karobi   +2 more
doaj   +1 more source

A random forest guided tour [PDF]

open access: yesTEST, 2016
The random forest algorithm, proposed by L. Breiman in 2001, has been extremely successful as a general-purpose classification and regression method. The approach, which combines several randomized decision trees and aggregates their predictions by averaging, has shown excellent performance in settings where the number of variables is much larger than ...
Biau, Gérard, Scornet, Erwan
openaire   +4 more sources

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

How do tour guides cope with knowledgeable tourists? Conceptualising knowledge/information asymmetry in tour-guiding contexts [PDF]

open access: yes
Purpose Tourists’ resource integration both offers opportunities and presents challenges to tourism service providers. Focussing on the tour guide perspective, this paper explores how tour guides experience knowledge/information-based asymmetry in ...
Rihova, Ivana, Alexander, Matthew
core   +1 more source

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