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An Update on Tourette Syndrome

Current Neurology and Neuroscience Reports, 2010
Recent advances in our understanding of the phenomenology, etiology, pathophysiology, and treatment of Tourette syndrome are discussed. Tourette syndrome appears to involve dysfunction of limbic and somatosensory "traffic" through the basal ganglia, within corticostriatal-thalamocortical circuits.
Thomas E. Kimber, Thomas E. Kimber
openaire   +4 more sources

Controlled stimulant treatment of ADHD and comorbid Tourette's syndrome: effects of stimulant and dose.

Journal of the American Academy of Child and Adolescent Psychiatry, 1997
OBJECTIVE To determine the effects of methylphenidate (MPH) and dextroamphetamine (DEX) on tic severity in boys with attention-deficit/hyperactivity disorder (ADHD) comorbid with Tourette's syndrome.
F. Castellanos   +6 more
semanticscholar   +1 more source

The pharmacology of Tourette syndrome

Journal of Neural Transmission, 2013
Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterised by multiple motor and vocal tics, plus associated behavioural symptoms. Tics are defined as sudden, rapid, repetitive non-rhythmic movements (motor tics) or vocalisations (vocal tics).
Andrea E. Cavanna   +2 more
openaire   +3 more sources

Elevated intrasynaptic dopamine release in Tourette's syndrome measured by PET.

American Journal of Psychiatry, 2002
OBJECTIVE Dopaminergic abnormalities in frontal-subcortical circuits have been hypothesized as the underlying pathophysiologic mechanism in Tourette's syndrome. The objective of this study was to test the hypothesis that presynaptic dopamine release from
H. Singer   +8 more
semanticscholar   +1 more source

Case study: a new infection-triggered, autoimmune subtype of pediatric OCD and Tourette's syndrome.

Journal of the American Academy of Child and Adolescent Psychiatry, 1995
A review of clinical observations and literature reports leads to the hypothesis that, via a process analogous to Sydenham's chorea, infections with group A beta-hemolytic streptococci, among others, may trigger autoimmune responses that cause or ...
A. Allen, H. Leonard, S. Swedo
semanticscholar   +1 more source

Tourette Syndrome

2011
Gilles de la Tourette syndrome, currently known as Tourette syndrome (TS) in the United States and much of the rest of the world, is a neurodevelopmental disorder characterized by the presence of multiple motor tics and at least one vocal/phonic tic. Originally described over a century ago, TS is increasingly recognized as a relatively common disorder,
Robertson MM, Cavanna A
openaire   +2 more sources

Tourette syndrome

2013
This chapter addresses research applications of transcranial magnetic stimulation (TMS) in Tourette syndrome (TS). TS is a primary, idiopathic, neurological disorder characterized by multiple motor and vocal tics of childhood onset, with duration greater than 1 year, and associated in the majority of cases with attention-deficit/hyperactivity disorder (
Donald L. Gilbert, Nasrin Shahana
openaire   +3 more sources

Risperidone versus clonidine in the treatment of children and adolescents with Tourette's syndrome.

Journal of the American Academy of Child and Adolescent Psychiatry, 2002
OBJECTIVE To evaluate the efficacy and tolerability of risperidone in comparison with clonidine in the treatment of children and adolescents with Tourette's syndrome (TS).
G. Gaffney   +5 more
semanticscholar   +1 more source

Gilles de la Tourette's syndrome and obsessive-compulsive disorder. Evidence supporting a genetic relationship.

Archives of General Psychiatry, 1986
Previous studies have suggested that obsessive-compulsive symptoms frequently occur among patients with Gilles de la Tourette's syndrome (TS). To examine the relationship between TS and obsessive-compulsive disorder (OCD), data from all first-degree ...
D. Pauls   +4 more
semanticscholar   +1 more source

Surgery for Tourette Syndrome

World Neurosurgery, 2013
Tourette syndrome is a chronic neuropsychiatric disorder characterized by motor and vocal tics. In the majority of cases, tics are associated by behavioral disorders such as obsessive-compulsive behavior. First symptoms typically appear in early childhood. Mostly symptoms disappear when adulthood is reached.
Jens Kuhn   +4 more
openaire   +3 more sources

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