Results 121 to 130 of about 2,254,790 (241)
Methylphenidate in Treatment of ADHD and Comorbid Chronic Tic Disorder
The safety and efficacy of immediate-release methylphenidate (MPH-IR) for the treatment of attention deficit hyperactivity disorder (ADHD) in children (ages 6-12 years) with Tourette's syndrome (96%) or chronic motor tic disorder (4%) were evaluated at ...
J Gordon Millichap
doaj +1 more source
A drug repurposing screen for reactive oxygen species (ROS)‐inducing compounds identified Pimozide as a potent anti‐tumor agent in head and neck squamous cell carcinoma (HNSCC) patient‐derived xenograft (PDX) models. Combined treatment with paclitaxel markedly reduced undifferentiated tumor cells.
Shogo Okazaki +12 more
wiley +1 more source
The Effect of Ecopipam on the Pharmacokinetics of Concomitant Medications
ABSTRACT Ecopipam is a first‐in‐class dopamine D1 receptor antagonist under investigation for the treatment of Tourette syndrome. This open‐label, fixed‐sequence, three‐cohort study evaluated whether ecopipam induces or inhibits cytochrome P450 (CYP) 1A2, CYP2B6, CYP2C19, CYP2D6, CYP3A4, organic anion‐transporting polypeptide (OATP) 1B1, and p ...
Virginia D. Schmith +4 more
wiley +1 more source
The deconstruction of Gilles de la Tourette’s syndrome
The present deconstruction of Gilles de la Tourette’s Syndrome introduces this complex disorder using an existential paradigm. An analysis of the history of constructed reason and power highlights the assumptions of ‘disorder’ that infiltrate society and
Rowan Voirrey Sandle
doaj +1 more source
The validity of instruments measuring tic severity in Tourette's syndrome.
By using four different scales that measure tic severity in Tourette's syndrome, three independent judges concurrently evaluated their validity and interjudge reliability in 20 affected individuals. The Yale Global Tic Severity Scale, Tourette's Syndrome
J. Walkup +3 more
semanticscholar +1 more source
The incidence of developmental disorders and special educational needs (SEN) provision were investigated, and associations with gestational age and ethnicity were explored, using the Born in Bradford cohort. Birth before full term was associated with increased odds of developmental disorder and/or SEN, which was even demonstrated in early term (37–38 ...
Katherine Pettinger +4 more
wiley +1 more source
Tourette's syndrome is a disease from the borderlands of psychiatry and neurology. Its course consists of chronic motor tics, vocal tics or vocalizations. The first symptoms appear in childhood or adolescence. Tics may cause body injuries.
Jaromir Kargol +4 more
doaj +1 more source
Malignant Tourette's Syndrome in an Adult on Deep Brain Stimulation Presenting With Rhabdomyolysis. [PDF]
Monga V, Madan R, Arora N.
europepmc +1 more source
In children potentially fulfilling the criteria for developmental coordination disorder (DCD), phenotypical assessment does not sufficiently predict the diagnostic outcome (i.e. DCD or an alternative diagnosis). Due to the lack of distinguishing clinical and diagnostic features and the high prevalence of genetic diagnoses in these patients, additional ...
Martinica Garofalo +5 more
wiley +1 more source

