Results 11 to 20 of about 12,296 (207)

Synaptic processes and immune-related pathways implicated in Tourette syndrome.

, 2021
Tourette syndrome (TS) is a neuropsychiatric disorder of complex genetic architecture involving multiple interacting genes. Here, we sought to elucidate the pathways that underlie the neurobiology of the disorder through genome-wide analysis. We analyzed
Leckman, J.F., Song, J., Hebebrand, J., Coffey, B.J., Jankovic, J., Madruga-Garrido, M., Müller-Vahl, K., Garcia-Delgar, B., Cheon, K.A., Dietrich, A., Mathews, C.A., Sul, J.H., Brown, L., Kook, S., Berlin, C., Neale, B.M., Hedderly, T., Huang, A.Y., Schlögelhofer, M., Darrow, S., Cath, D.C., Wolanczyk, T., Konstantinidis, A., Nöthen, M.M., Lyon, G.J., Brown, L.W., Woods, D.W., Hoekstra, P.J., Mir, P., Shin, E.Y., Budman, C.L., Rizzo, R., Darrow, S.M., Heiman, G.A., Kurlan, R., Davis, L.K., McMahon, W.M., Tischfield, J., Singer, H.S., Dion, Y., Hinney, A., Sandor, P., Worbe, Y., Song, D.H., Plessen, K.J., Smit, J.H., Münchau, A., Yu, D., Scharf, J.M., Zinner, S.H., Depienne, C., Barta, C., Hirschtritt, M.E., Koh, Y.J., Fernandez, T., Roessner, V., Hoekstra, P., Nagy, P., Jeremy Willsey, A., Heyman, I., Grice, D.E., Batterson, J.R., Illmann, C., Heiman, G., Barr, C.L., Grados, M.A., Kim, Y.S., Stuhrmann, M., Leventhal, B.L., Tischfield, J.A., Kim, Y.K., Wagner, M., Zinner, S., Muller-Vahl, K.R., Tarnok, Z., Gilbert, D.L., Tsetsos, F., Aschauer, H., Hartmann, A., Gilbert, D., Osiecki, L., Greenberg, E., Paschou, P., Freimer, N.B., Stamenkovic, M., Huyser, C., Okun, M.S., Knowles, J.A., Cox, N.J., Fernandez, T.V., Malaty, I.A., Woods, D., King, R.A., Coppola, G., Willsey, A.J., Rouleau, G.A., Aschauer, HAH, Morer, A., Hagstrøm, J., Lee, P.C., Kuperman, S., Robertson, M.M.   +101 more
core   +1 more source

The relationship between group A streptococcal infections and Tourette syndrome: a study on a large service-based cohort

, 2011
AIM To evaluate the relationship between diagnosis and clinical course of Tourette syndrome and group A Streptococcus (GAS). METHOD GAS infections, anti-streptococcal, and anti-basal ganglia antibodies (ABGA) were compared between 168 patients (136 males,
Maura Buttiglione, Edvige Veneselli, Davide Martino, Flavia Chiarotti, Graziella Orefici, Renata Rizzo, Roberta Creti, N. Nardocci, CARDONA, Francesco Carmelo Giovanni, O. N. Syndrome Study Group Behalf Of The Italian Tourette   +9 more
core   +2 more sources

Parent and self-report health-related quality of life measures in young patients with Tourette syndrome

, 2013
Tourette syndrome is a neurodevelopmental disorder characterized by tics and comorbid behavioral problems. This study compared child- and parent-reported quality of life and everyday functioning.
C. Luoni, C. Selvini, A. E. Cavanna, Blangiardo, R, Cali', PV, Blangiardo, Rosanna, CARDONA, Francesco Carmelo Giovanni, Rizzo, R, TERMINE, CRISTIANO, Eddy, Clare M, Selvini, Claudia, Cardona, Francesco, Gagliardi, E, SILVESTRI, PAOLA ROSARIA, U. Balottin, Silvestri, Paola R., BALOTTIN, UMBERTO, E. Gagliardi, Cardona, F, Cavanna, Andrea E., Gagliardi, Emanuela, Cali', Paola V., Cavanna, Andrea E; id_orcid, Cavanna, AE, Eddy, CM, Balottin, U, C. M. Eddy, P. V. Cali', Silvestri, Paola R, Luoni, C, Termine, C, Eddy, Clare M., Rizzo, Renata, C. Termine, Silvestri, PR, R. Blangiardo, Cali', Paola V, R. Rizzo, Luoni, Chiara, Selvini, C   +39 more
core   +1 more source

Stigma in youth with Tourette's syndrome: a systematic review and synthesis [PDF]

, 2015
Tourette's syndrome (TS) is a childhood onset neurodevelopmental disorder, characterised by tics. To our knowledge, no systematic reviews exist which focus on examining the body of literature on stigma in association with children and adolescents with TS.
Forrester-Jones, Rachel, Murphy, Glynis, Malli, Melina A, Malli, M., Murphy, Glynis H.   +4 more
core   +1 more source

Alternative Treatments in Tourette Syndrome

, 2013
Complementary and alternative medicine (CAM) approaches are among the most popular and widely used treatments for Tourette syndrome (TS). This chapter is a systematic and critical review of the scattered evidence available on this topic.
Zolovska, Beata, Coffey, Barbara J, Barbara J. Coffey, Beata Zolovska   +3 more
core   +1 more source

A Systematic Review of the Safety and Tolerability of Theta Burst Stimulation in Children and Adolescents

Neuromodulation: Technology at the Neural Interface, EarlyView., 2021
Abstract Objectives Theta burst stimulation (TBS) is often used in clinical practice and research protocols for adults with neuropsychiatric disorders. There are substantial knowledge gaps related to the application of TBS in children and adolescents.
Rana Elmaghraby, Qi Sun, Can Ozger, Julia Shekunov, Magdalena Romanowicz, Paul E. Croarkin   +5 more
wiley   +1 more source

Defining Features of Gabriele‐de Vries Syndrome in Adults: A Case Report and Literature Review

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gabriele‐de Vries syndrome (GADEVS) is a neurodevelopmental disorder caused by heterozygous pathogenic variants in the YY1 gene. Like most rare genetic syndromes, the adult manifestations of GADEVS remain poorly defined. Here, we describe the oldest patient reported to date with GADEVS—a 63‐year‐old woman with a c.1177_1179del YY1 variant ...
Ethan W. Hollingsworth, Changrui Xiao
wiley   +1 more source

A Global Prospective Harmonization Framework for Suicidality, Anhedonia, and Obsessive‐Compulsive Symptoms in Psychiatric Genetic Studies: A Cross‐Continental Study Within the Ancestral Population Network

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, EarlyView.
ABSTRACT This study aims to prospectively collect harmonized, quantitative, and dimensional psychiatric phenotypes (suicidality, anhedonia, and obsessive‐compulsive symptoms) and information on discrimination, stigma, and unfair treatment in up to 27,500 individuals across diverse ancestries and clinical populations for genetic analysis within the NIMH
Ana M. Diaz‐Zuluaga, Jacey L. Anderberg, Ana M. Ramirez‐Diaz, Andrea Horvath Marques, Catherine E. Rast, Daniel Bustamante, Deborah Jonker, Johanna Valencia‐Echeverry, Joseph Kyebuzibwa, Josselyn S. Muñoz, Kristien van der Walt, Mauricio Castaño Ramirez, Olivia Wootton, Renee M. Frederick, Rocky E. Stroud II, Ruben Gur, Sang Jin Rhee, Shaili C. Jha, Stella Gichuru, Susan Service, Victor I. Reus, Akena Dickens, Carlos Lopez‐Jaramillo, Carrie E. Bearden, Dan J. Stein, Ezra S. Susser, James J. Crowley, Jonathan Flint, Kenneth S. Kendler, Lukoye Atwoli, Michele T. Pato, Nelson B. Freimer, Roel A. Ophoff, Yong Min Ahn, Loes Olde Loohuis, Eric A. Storch, Bizu Gelaye   +36 more
wiley   +1 more source

Judicial Perspectives on Neurodiversity in Queensland Courts, Tribunals and Commissions: Experiences With Disclosure and Witness Credibility

Australian Journal of Social Issues, EarlyView.
ABSTRACT Little is known about the impacts of the disclosure, or the non‐disclosure, of medical conditions associated with neurodiversity in the context of court proceedings and hearings before tribunals and commissions. This paper examines the experiences of twenty‐three Queensland Judges, Magistrates, and Tribunal and Commission Members with ...
Danielle Bozin, Karen A. Sullivan, Vincent Denault, Catherine Kennon, Lucy Cradduck, Rachel Hews   +5 more
wiley   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

Biological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater, Adam Dušek, Aleksandra Bartelik, Silvia Mandillo, Elisabetta Golini, Mara Rigamonti, Rasneer Sonia Bains, Hamish Forrest, Marion Rivalan, Melissa Long, Anna Kiryk, Lars Lewejohann, Nuno Henrique Franco   +12 more
wiley   +1 more source