Results 51 to 60 of about 41,534 (269)

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

THE MAIN CHALLENGES OF DUAL VOCATIONAL EDUCATION AND TRAINING SYSTEM TRANSFER

open access: yesEducation: Modern Discourses, 2022
Developing countries need practical VET systems that will meet the needs of the economic sector. Ukraine is making efforts to introduce a dual system of vocational education and training and has already faced many challenges in this process.
Лариса Гончар
doaj   +1 more source

The Tourists

open access: yesDesign/Arts/Culture
"The Tourists" is a subversive tourism campaign by the Depression Era collective, reflecting on the simultaneous influx of refugees and global tourism in Southern Europe. Through diverse media, it exposes landscapes marked by hidden violence, portrays individuals in states of flux, and blurs the line between idyllic tourism and harsh reality.
Vorgia, Pasqua, Babasikas, Petros
openaire   +2 more sources

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp   +4 more
wiley   +1 more source

Program Specification of Musical Training in the Graeco-Roman Egypt [PDF]

open access: yesInternational Journal of Tourism and Hospitality Management, 2020
Music plays a vital role in Greek civilization and it considered nutrition for the sole of human. Philosophers considered it a mean to be more civilized.
Doaa Ahmed
doaj   +1 more source

Anti‐CD20 Discontinuation Versus Continuation in People Aged Over 50 With Non‐Active Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine whether discontinuing anti‐CD20 therapy in people with relapsing‐onset MS aged over 50 is associated with an increased risk of relapse, inflammatory activity, confirmed disability accrual, and serious infection compared with continuing therapy.
Alexia Moukhine   +40 more
wiley   +1 more source

Section One of Chapter 127 of the Book of the Dead and the Deities of the Cavern Investigated [PDF]

open access: yesالمجلة العلمیة لکلیة السیاحة والفنادق جامعة الأسکندریة, 2020
The current work investigates section one of BD 127 and their deities i.e. the deities of the caverns. Thus, this article is divided into two parts. Part one will focus on the BD 127 including an analysis of the first section, presenting various rubrics ...
Amr Gaber
doaj   +1 more source

Advances in Sustainable and Wearable Textile Based Soft Robotics

open access: yesAdvanced Functional Materials, EarlyView.
This Review examines advances in wearable textile‐based soft robotics, focusing on sustainable materials, integrated sensing, and scalable actuation. It discusses manufacturing and system integration across healthcare, assistive robotics, prosthetics, and human–machine interfaces, and highlights key challenges in circular design, including life‐cycle ...
Zahir Abbas   +6 more
wiley   +1 more source

Relationship between Recreational Greenway Involvement and Residents' Loyalty and Environmental-Responsibility Behavior: A Case Study of Zengcheng Greenway, Guangzhou

open access: yesRedai dili, 2023
Situational factors affect the continuation and spillover of individual emotions and behavior. People's environmental-responsibility behavior in ecotourism situations can be difficult to extend to everyday life.
Wu Zhicai, Wang Bowen, Liu Jiaman
doaj   +1 more source

High‐Performance n‐Type Organic Thermoelectrics Enabled by Control Over Microstructure, Orientation and Contact Plane in Naphthalenediimide‐Bithiazole‐Copolymer Films

open access: yesAdvanced Functional Materials, EarlyView.
Effective control over the crystalline contact plane and microstructure of a naphthalenediimide‐bithiazole copolymer enables high‐performance n‐type thermoelectrics. While rubbing alignment induces a detrimental edge‐on orientation, subsequent solvent vapor‐induced re‐orientation facilitates a favorable mixed face‐on/edge‐on morphology.
Suhao Wang   +13 more
wiley   +1 more source

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