Results 91 to 100 of about 21,827,196 (263)
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
[Singing Tower construction site : version 01]
, 2014 eye-level views;A negative showing the site of Mountain Lake Sanctuary's (now Bok Tower Gardens) Singing Tower prior to construction. Stakes are visible in the ground likely marking the base of the Tower.
Burrell, Horace H.;
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FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
[Singing Tower construction site : version 04]
, 2014 eye-level views;This is an image of a machine, possibly a winch, used in the construction of the Singing Tower at Mountain Lake Sanctuary (now Bok Tower Gardens). '3-19-27' appears at the bottom of the negative.
Burrell, Horace H.;
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FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
, 2015 The 205 foot steel skeleton of the Bok singing Tower, Lake Wales, Fla., photographed during construction on Nov.
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BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
Setting stone and brick for the construction of the Bok Singing Tower
, 2018 eye-level views;Photograph showing the construction of the Bok Singing Tower. Crates of stone scattered around the northwest side of the tower. Several working structures and ramps leading into the tower.
Alexander, Arthur L., 1856-1947
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FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
, 2015 The Singing Tower from the North, Lake Wales, Florida. The Mountain Lake Singing Tower is located on the highest land in Florida and it is surrounded by 46 acres of beautifully landscaped grounds - the Sanctuary.
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