Results 121 to 130 of about 418,742 (295)

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

Failure Risk Investigation of Transmission Tower-line System Under Sequential Earthquake Considering Input Directionality

工程科学与技术
ObjectiveTransmission tower-line structures are representative spatial distribution systems. They typically span hundreds or even thousands of kilometers and inevitably traverse regions with high seismic intensities.
LIU Juncai, DONG You
doaj  

Influence of temperature effects on the pylon-beam support system of cable-stayed bridges

Shenzhen Daxue xuebao. Ligong ban
In order to explore the stress characteristics of a single-tower multi-span cable-stayed bridge under system temperature effects, taking a multi-span cable-stayed bridge project as an example, a full-bridge finite element model is established based on ...
ZHAO Licai
doaj   +1 more source

Anomalies in the Entanglement Properties of the Square Lattice Heisenberg Model

, 2013
We compute the bipartite entanglement properties of the spin-half square-lattice Heisenberg model by a variety of numerical techniques that include valence bond quantum Monte Carlo (QMC), stochastic series expansion QMC, high temperature series ...
A. W. Sandvik, Ann B. Kallin, J. Oitmaa, Matthew B. Hastings, Rajiv R. P. Singh, Roger G. Melko   +5 more
core   +1 more source

Developmental, Neuroanatomical and Cellular Expression of Genes Causing Dystonia

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most common movement disorders, with variants in multiple genes identified as causative. However, an understanding of which developmental stages, brain regions, and cell types are most relevant is crucial for developing relevant disease models and therapeutics.
Darren Cameron, Nicholas E. Clifton, Daniel Cabezas de la Fuente, Peter Holmans, Nicholas J. Bray, Kathryn J. Peall   +5 more
wiley   +1 more source

Parametric Study of Tuned Mass Dampers for Long Span Transmission Tower-Line System under Wind Loads

Shock and Vibration, 2016
A parametric study of tuned mass dampers for a long span transmission tower-line system under wind loads is done in this paper. A three-dimensional finite element model of transmission tower-line system is established by SAP2000 software to numerically ...
Li Tian, Yujie Zeng
doaj   +1 more source

Microgravity experiments on the collisional behavior of Saturnian ring particles

, 2009
In this paper we present results of two novel experimental methods to investigate the collisional behavior of individual macroscopic icy bodies. The experiments reported here were conducted in the microgravity environments of parabolic flights and the ...
Albers, Araki, Araki, Blum, Borderies, Bridges, Brilliantov, Brilliantov, Brito, Colwell, Colwell, Colwell, Colwell, Daniel Heißelmann, Dilley, Esposito, Goldhirsch, Goldreich, Grasselli, Haff, Hameen-Anttila, Hatzes, Hedman, Helen J. Fraser, Higa, Higa, Jürgen Blum, Kristin Wolling, Langkowski, Marouf, Miller, Porco, Poulet, Salo, Salo, Salo, Salter, Schmidt, Sorace, Spahn, Spahn, Supulver, Thomson, Tiscareno, Trulsen, Trulsen, Tyler, Wisdom, Zebker   +48 more
core   +1 more source

Super‐Refractory Status Epilepticus (SRSE) in a Patient With Compound Heterozygous OPA1 Variants: Case Report and Literature Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi, Lara Basovic, Christopher Michael McGraw   +2 more
wiley   +1 more source

ALS With and Without Upper Motor Neuron Signs: A Comparative Study Supporting the Gold Coast Criteria

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The Gold Coast criteria permit diagnosis of amyotrophic lateral sclerosis (ALS) even without upper motor neuron (UMN) signs. However, whether ALS patients with UMN signs (ALSwUMN) and those without (ALSwoUMN) share similar characteristics and prognoses remains unclear.
Hee‐Jae Jung, E‐nae Cheong, Jungmin So, Heung‐Won Kang, Yangsean Choi, Eun‐Jae Lee, Hyunjin Kim, Young‐Min Lim   +7 more
wiley   +1 more source

Prediction of low frequency and impulsive sound radiation from horizontal axis wind turbines [PDF]

, 1981
Theoretical models to predict the radiation of low frequency and impulsive sound from horizontal axis wind turbines due to three sources: (1) steady blade loads; (2) unsteady blade loads due to operation in a ground shear; (3) unsteady loads felt by the ...
Harris, W. L., Martinez, R., Widnall, S. E.   +2 more
core   +1 more source