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Correction: Immune checkpoint inhibitor-related Stevens-Johnson syndrome and toxic epidermal necrolysis: a retrospective analysis of 21 cases. [PDF]
Front ImmunolPu T, Teng Y, Zhang Y, Da M, Wang F.
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Lancet, The, 1998
1coined the term necrolysis to describe four clinical cases characterised pathologically by necrosis of the epidermis, and clinically by widespread epidermolysis—a loosening of the epidermis leading to blister formation, exfoliation, or both. Large sheets of skin had peeled off, leaving a raw, denuded base.
exaly +3 more sources
1coined the term necrolysis to describe four clinical cases characterised pathologically by necrosis of the epidermis, and clinically by widespread epidermolysis—a loosening of the epidermis leading to blister formation, exfoliation, or both. Large sheets of skin had peeled off, leaving a raw, denuded base.
exaly +3 more sources
International Journal of Dermatology, 1991
Toxic Epidermal Necrolysis (TEN) is an acute, severe, often life-threatening skin reaction, which is characterized by an extensive necrosis and detachment of the epidermis and mucous membranes. It has been observed worldwide and affects people of both sexes and all ages.
T E, Rohrer, A R, Ahmed
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Toxic Epidermal Necrolysis (TEN) is an acute, severe, often life-threatening skin reaction, which is characterized by an extensive necrosis and detachment of the epidermis and mucous membranes. It has been observed worldwide and affects people of both sexes and all ages.
T E, Rohrer, A R, Ahmed
+10 more sources
Postgraduate Medicine, 1972
Toxic epidermal necrolysis, although uncommon, warrants the attention of all clinicians because of its serious prognosis. The clinical course of this cutaneous syndrome is similar in children and adults, but some differences do exist. Because diagnostic laboratory tests are not available, the physician must recognize the disorder by its distinctive ...
A J, Ammann, W H, Tooley, R, Hong
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Toxic epidermal necrolysis, although uncommon, warrants the attention of all clinicians because of its serious prognosis. The clinical course of this cutaneous syndrome is similar in children and adults, but some differences do exist. Because diagnostic laboratory tests are not available, the physician must recognize the disorder by its distinctive ...
A J, Ammann, W H, Tooley, R, Hong
+7 more sources
Current Drug Safety, 2012
Toxic epidermal necrolysis (TEN) is a severe mucocutaneous drug-induced syndrome that causes massive keratinocyte apoptosis and therefore hydro-electrolytic disorders and systemic infection. TEN approximately affects one to two cases per million per year. Mortality rate may reach thirty percent of cases. Thus, TEN constitute a therapeutic emergency at
Florence, Castelain, Philippe, Humbert
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Toxic epidermal necrolysis (TEN) is a severe mucocutaneous drug-induced syndrome that causes massive keratinocyte apoptosis and therefore hydro-electrolytic disorders and systemic infection. TEN approximately affects one to two cases per million per year. Mortality rate may reach thirty percent of cases. Thus, TEN constitute a therapeutic emergency at
Florence, Castelain, Philippe, Humbert
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International Journal of Dermatology, 1996
Abstract Background. Most studies on drug‐induced toxic epidermal necrolysis (TEN) report a high mortality rate. This has been attributed partly to the use of corticosteroids for its treatment. However, we consider corticosteroids to be the sheet anchor for saving the patients having TEN. Materials and Methods.
J S, Pasricha +4 more
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Abstract Background. Most studies on drug‐induced toxic epidermal necrolysis (TEN) report a high mortality rate. This has been attributed partly to the use of corticosteroids for its treatment. However, we consider corticosteroids to be the sheet anchor for saving the patients having TEN. Materials and Methods.
J S, Pasricha +4 more
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Journal of Burn Care & Rehabilitation, 1997
Toxic epidermal necrolysis (TEN) is a poorly understood and devastating condition. It is usually diagnosed in a primary care setting. Treatment of severe cases by burn care personnel is usually by referral. In this review, we report excessive mortality rates associated with prolonged use of systemic steroid therapy and delayed referral (more than 1 ...
J T, Murphy, G F, Purdue, J L, Hunt
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Toxic epidermal necrolysis (TEN) is a poorly understood and devastating condition. It is usually diagnosed in a primary care setting. Treatment of severe cases by burn care personnel is usually by referral. In this review, we report excessive mortality rates associated with prolonged use of systemic steroid therapy and delayed referral (more than 1 ...
J T, Murphy, G F, Purdue, J L, Hunt
openaire +2 more sources