Results 51 to 60 of about 8,783 (182)
Important Points in Toxic Epidermal Necrolysis Management
Oman Medical Journal, 2019 There are several important points that the authors did not highlight which are critical and form the cornerstones in the care of patients with possible TEN.
Sultan
doaj +1 more source
Multidisciplinary Treatment in Toxic Epidermal Necrolysis
International Journal of Environmental Research and Public Health, 2023 Toxic epidermal necrolysis, Leyll’s syndrome (TEN), is a rare mucocutaneous blistering disease burdened with high mortality rates. The diagnosis of TEN is based on clinical symptoms and histopathological findings. In approximately 90% of cases, it is a severe adverse reaction to drugs.
Agnieszka Surowiecka +2 more
openaire +3 more sources
Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He +11 more
wiley +1 more source
Toxic epidermal necrolysis in a 5-year-old boy - case report
Brazilian Dental Science, 2016 Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered a spectrum of acute life-threatening mucocutaneous reaction that differ only in severity, often induced by drugs.
Pavan Puri +5 more
doaj +1 more source
Cutaneous approach in toxic epidermal necrolysis [PDF]
Revista Brasileira de Cirurgia Plástica, 2017 INTRODUCTION: Toxic epidermal necrolysis is a severe acute mucocutaneous condition usually induced by drugs associated with a high rate of morbidity and mortality.
Francisco Carlos Santos Neto +6 more
doaj +1 more source
Journal of Cutaneous Pathology, EarlyView.ABSTRACT Background Frozen section analysis enables rapid diagnosis, but its diagnostic accuracy in the setting of severe cutaneous adverse reactions (SCARs) remains poorly defined. Methods A systematic review and meta‐analysis were performed to evaluate the diagnostic performance of frozen sections in the rapid identification of SCARs, with a focus on
Cody C. Frear +3 more
wiley +1 more source
Toxic Epidermal Necrolysis Associated with Misoprostol: A Case Report
International Medical Case Reports Journal, 2023 Okbu Frezgi,1 Mulugeta Russom2– 4 1Gynecology and Obstetric Unit, Orotta College of Medicine and Health Sciences, Asmara, Eritrea; 2Eritrean Pharmacovigilance Centre, National Medicines and Food Administration, Ministry of Health, Asmara, Eritrea ...
Frezgi O, Russom M
doaj
Effect and length of doxycycline administration in elderly patients with bullous pemphigoid
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background Bullous pemphigoid (BP) is the most common autoimmune blistering disease and primarily affects the elderly. Systemic corticosteroids and immunosuppressive drugs are the standard treatment, but side effects often restrict their use. Doxycycline has been proposed as an alternative, but there is limited long‐term, real‐world data on its
Alena Merkel‐Ropele +2 more
wiley +1 more source
Case Reports in Immunology, 2012 Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and ...
Carlos Saavedra +4 more
doaj +1 more source
Toxic Epidermal Necrolysis in an Irradiated Patient Treated with a Nanocrystalline Silver Dressing
Case Reports in Dermatology, 2012 Toxic epidermal necrolysis syndrome is a severe exfoliative condition, which may be triggered by anticonvulsant medication. We report a case of toxic epidermal necrolysis syndrome in a 43-year-old female who was receiving radiotherapy for brain ...
Tamara Z. Vern-Gross +2 more
doaj +1 more source