Results 11 to 20 of about 638,455 (170)
Lamotrigine, a Miscreant in Toxic Epidermal Necrolysis: A Rare Case Report [PDF]
, 2023 This case report is about a rural 39 years old female of Asian origin and laborer by profession who developed Toxic Epidermal Necrolysis (TEN) with lamotrigine.
Mahima MAKHIJA +2 more
core +2 more sources
Case Report on Phenytoin-Induced Toxic Epidermal Necrolysis [PDF]
, 2022 Toxic epidermal necrolysis is a cutaneous drug reaction which is a severe adverse effect that predominantly involves the skin and mucous membrane. Phenytoin is an anti-epileptic medication that belongs to the hydantoin class. Here we are going to present
David, Nishoja +2 more
core +1 more source
Dermatology Reports, 2023 The treatment of epidermal necrolysis in pediatric patients remains a major challenge. Cyclosporine A has emerged as a promising therapy for epidermal necrolysis in adults; however, its efficacy in children is unclear.
Shinta Trilaksmi Dewi +8 more
doaj +1 more source
Toxic epidermal necrolysis [PDF]
F1000Research, 2016 Toxic epidermal necrolysis (TEN) is a rare, life-threatening drug-induced skin disease with a mortality rate of approximately 30%. The clinical hallmark of TEN is a marked skin detachment caused by extensive keratinocyte cell death associated with mucosal involvement. The exact pathogenic mechanism of TEN is still uncertain.
Hoetzenecker, Wolfram +7 more
openaire +4 more sources
Pembrolizumab-Induced Toxic Epidermal Necrolysis
Case Reports in Oncology, 2022 Immunotherapy has nowadays become part of the mainstay of treatment for several cancers. In this report, we present a case of toxic epidermal necrolysis (TEN) occurring as a relatively rare complication of pembrolizumab, which is a humanized monoclonal ...
Luca Borg +5 more
doaj +1 more source
Stevens Johnson Syndrome/Toxic Epidermal Necrolysis and Erythema Exsudativum Multiforme [PDF]
, 2022 In the past, definition and name giving of erythema exsudativum multiforme, Stevens-Johnson syndrome and toxic epidermal necrolysis have been confusing.
Kardaun, Sylvia H., Sylvia H. Kardaun
core +1 more source
Burns Open, 2017 Toxic epidermal necrolysis (TEN) represents the most serious affection within the SCARs group (Severe Cutaneous Adverse Reactions). It is an autoimmune disease manifested by extensive epidermal and mucosal exfoliation.
B. Lipový +8 more
doaj +1 more source
Identifying the incidence of rash, Stevens-Johnson syndrome and toxic epidermal necrolysis in patients taking lamotrigine: a systematic review of 122 randomized controlled trials [PDF]
Anais Brasileiros de Dermatologia, 2017 Lamotrigine is an antiepileptic drug used for the treatment of epilepsy, bipolar disorder and numerous off-label uses. The development of rash significantly affects its use. The most concerning of these adverse reactions is Stevens-Johnson syndrome/toxic
Romi Bloom, Kyle T. Amber
doaj +2 more sources
The Journal of Emergency Medicine, 1989 Toxic epidermal necrolysis (TEN) is a life-threatening condition in which the epidermis blisters and peels in large sheets. The clinical syndrome and diagnosis are reviewed. Current treatment and prevention of complications are discussed. The key to low morbidity and mortality in TEN is early intervention.
Department of Medicine, Medical College of Georgia, Augusta, Georgia, USA ( host institution ) +4 more
openaire +5 more sources
Toxic epidermal necrolysis caused by flurazepam?
, 2005 Stevens-Johnson syndrome and toxic epidermal necrolysis are rare, but severe cutaneous reactions. Beside cutaneous manifestations, the syndrome is characterised by constitutional sypmtoms with even lethal consequences.
Bilusić, Marijo +2 more
core +3 more sources