Results 71 to 80 of about 524,357 (214)
INtraVESical immunoTherapy (INVEST) prior to radical cystectomy for bladder cancer: trial protocol
Background High‐risk non‐muscle‐invasive bladder cancer (HRNMIBC) has a variable prognosis, managed predominantly by local surgical resection and intravesical Bacillus Calmette–Guérin (BCG), or radical cystectomy (RC). Current treatments are poorly tolerated, have supply limitations and often fail to control the disease.
Ruby Lister‐Whelan +13 more
wiley +1 more source
Fatal Phenytoin-Related Toxic Epidermal Necrolysis: Case Report
Toxic epidermal necrolysis is a rare but often fatal hypersensitivity reaction to numerous agents, including most anticonvulsants. The authors present a case of fatal phenytoin-related toxic epidermal necrolysis in a patient who was given prophylactic ...
Daniel F. Kelly, Donald G. Hope
core +1 more source
Toxic epidermal necrolysis in a 5-year-old boy - case report
Toxic epidermal necrolysis (TEN) and Stevens-Johnson syndrome (SJS) are considered a spectrum of acute life-threatening mucocutaneous reaction that differ only in severity, often induced by drugs.
Pavan Puri +5 more
doaj +1 more source
Farmacodermias no Hospital Universitário: 5 anos de estudo [PDF]
Trabalho de Conclusão de Curso - Universidade Federal de Santa Catarina. Curso de Medicina.
Fischer, Bruna Copstein
core
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti +7 more
wiley +1 more source
Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and ...
Carlos Saavedra +4 more
doaj +1 more source
Toxic Epidermal Necrolysis in an Irradiated Patient Treated with a Nanocrystalline Silver Dressing
Toxic epidermal necrolysis syndrome is a severe exfoliative condition, which may be triggered by anticonvulsant medication. We report a case of toxic epidermal necrolysis syndrome in a 43-year-old female who was receiving radiotherapy for brain ...
Tamara Z. Vern-Gross +2 more
doaj +1 more source
Dermatologic Toxicities Associated With Novel Pan‐RAS/RAF Inhibitors
ABSTRACT Background The mitogen‐activated protein kinase (MAPK) pathway plays a key role in cell‐cycle regulation and tumor progression in cancer. Dermatologic toxicities (DTs) to newer pan‐RAS (RMC‐6236) and pan‐RAF (LXH254/naporafenib) inhibitors are emerging.
Lin J. He +11 more
wiley +1 more source
Objective: To recognize the common ocular signs and symptoms of toxic epidermal necrolysis (TEN), differentiate it from similar diseases, give the appropriate management, and provide continuity of care.
Rosalie Mae M. Reyes, MD +1 more
doaj
Deep cutaneous Trichosporon asahii infection in a patient recovering from toxic epidermal necrolysis
Patients with toxic epidermal necrolysis, a condition that causes full thickness epidermal necrosis that affects over 30% of the skin surface and mucosal membranes, often develop comorbid infections throughout the recovery of the disease [1].
John L. Kiley +4 more
doaj +1 more source

