Results 111 to 120 of about 1,068 (138)
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Archives of Dermatology, 1960
A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1or epidermolysis necroticans combustiformis by Soltermann.2Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3However, no recent ...
B, POTTER, R, AUERBACH, A L, LORINCZ
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A striking dermatologic disease resembling scalding, namely acute pemphigus, has been recently renamed toxic epidermal necrolysis by Lyell,1or epidermolysis necroticans combustiformis by Soltermann.2Already, mention has been made in the literature of a score or more examples under these names, and the disease is apparently not rare.3However, no recent ...
B, POTTER, R, AUERBACH, A L, LORINCZ
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Advances in toxic epidermal necrolysis
Seminars in Cutaneous Medicine and Surgery, 1996On the basis of the clinicopathologic and causative characteristics, one can separate an erythema multiformis spectrum from a toxic epidermal necrolysis (TEN)-Stevens Johnson syndrome which is a drug induced disease. Despite a well-known clinical aspect, several cutaneous diseases may be mistaken for TEN.
J E, Revuz, J C, Roujeau
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Plasmapheresis in toxic epidermal necrolysis
International Journal of Dermatology, 1997Abstract Background The treatment of toxic epidermal necrolysis (TEN) is usually based on the removal of the offending drug(s), fluid replacement, nutritional support, and local management. The mortality and morbidity, however, remain high and the death rate may be reduced to 10% only in special centers that use biologic dressings. Plasma exchange (PE)
G C, Chaidemenos +5 more
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Current Opinion in Allergy & Clinical Immunology, 2013
Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions.
Haur-Yueh, Lee, Wen-Hung, Chung
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Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe adverse drug reactions. Once thought to be idiosyncratic and unpredictable, there has been significant progress made in the understanding of the pathomechanism and pharmacogenetics of such reactions.
Haur-Yueh, Lee, Wen-Hung, Chung
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Pharmacogenetics of toxic epidermal necrolysis
Expert Opinion on Pharmacotherapy, 2010Toxic epidermal necrolysis (TEN) and Stevens-Johnson Syndrome (SJS) are two of the most severe drug-induced cutaneous reactions. Advances in genome technologies have allowed researchers to identify genetic markers associated with this drug-associated event and these have provided a potential tool for prevention.Current updates of genetic biomarkers ...
Ming Ta Michael, Lee +3 more
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Intestinal toxic epidermal necrolysis
Gazzetta Medica Italiana Archivio per le Scienze Mediche, 2018Toxic epidermal necrolysis (TEN), also known as the Stevens-Johnson Syndrome (SJS), is defined as severe, lifethreatening mucocutaneous reactions, predominantly drug induced, but also associated with infectious diseases. Clinical manifestations consist of erythematous cutaneous lesions, with blister formation and epidermal detachment as a consequence ...
Cudia, Antonella +4 more
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Management of toxic epidermal necrolysis
Hospital Medicine, 2000Toxic epidermal necrolysis and Stevens–Johnson syndrome are rare, life-threatening drug reactions. Widespread epidermal necrosis and mucosal erosions lead to complications similar to those developing after extensive burns. Treatment is supportive. The role of steroids and other potential disease-modifying agents remains to be established by controlled ...
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The management of toxic epidermal necrolysis
Australasian Journal of Dermatology, 2012ABSTRACTThe mortality rate of Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) is high; approximately 5% for SJS and 25% for TEN. It is therefore vital for the treating physician to recognise SJS and TEN promptly through the identification of these diseases' characteristic clinical features so that the offending drug is promptly ...
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Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis: A Review of Diagnosis and Management
Medicina (Lithuania), 2021Kiran Motaparthi +2 more
exaly
A Review of the Systemic Treatment of Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis
Biomedicines, 2022Hua-Ching Chang +2 more
exaly