Results 41 to 50 of about 612,298 (206)
Fatal case of cephalexin-induced toxic epidermal necrolysis
SAGE Open Medical Case Reports, 2014 Purpose: To describe a case of toxic epidermal necrolysis likely caused by cephalexin with a review of the literature. Case: An 80-year-old male with a known allergy to cephalosporins, residing at a long-term acute care hospital, received cephalexin for ...
Matthew J Hafermann +3 more
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Кубанский научный медицинский вестникBackground. Stevens — Johnson syndrome and toxic epidermal necrolysis are severe diseases featuring lesions of the mucous membranes and skin, with a possible lethal outcome. These diseases are most often triggered by various infections and medications, e.
G. M. Nurtdinova +6 more
doaj +1 more source
Journal of Medical Case Reports, 2012 Introduction Toxic epidermal necrolysis lies within the spectrum of severe cutaneous adverse reactions induced by drugs, affecting skin and mucous membranes.
Kamal Tamer +3 more
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Intravenous -acetylcysteine in severe cutaneous drug reaction treatment: A case series
SAGE Open Medical Case Reports, 2020 Drug-induced serious adverse reaction is an unpleasant event with high rate of mortality. Stevens–Johnson Syndrome and toxic epidermal necrolysis are most common among the serious adverse drug reactions.
Md Jahidul Hasan, Raihan Rabbani
doaj +1 more source
Indian Dermatology Online Journal, 2022 We report two consecutive cases of toxic epidermal necrolysis presented to our emergency department in the past 5 months. Both patients had history of fever prior to the onset of skin manifestations and showed radiological findings suggestive of COVID-19
Shayna Aulakh +3 more
doaj +1 more source
Toxic epidermal necrolysis and Stevens-Johnson syndrome: a review
, 2011 The aims of this review are to summarize the definitions, causes, and clinical course as well as the current understanding of the genetic background, mechanism of disease, and therapy of toxic epidermal necrolysis and Stevens-Johnson ...
Mathias Nelle +5 more
core +1 more source
Review of Toxic Epidermal Necrolysis [PDF]
International Journal of Molecular Sciences, 2016 Toxic epidermal necrolysis (TEN) is a rare but life threatening mucocutaneous reaction to drugs or their metabolites. It is characterised by widespread keratinocyte apoptosis and sloughing of the skin, erosions of the mucous membranes, painful blistering, and severe systemic disturbance.
Victoria Harris +2 more
openaire +2 more sources
British Journal of Clinical Pharmacology, EarlyView.After HLA‐B*15:02 screening, the residual risk of carbamazepine‐induced nonimmediate cutaneous adverse reactions is 0.059. Among these HLA‐B*15:02‐negative cases, HLA‐B*15:11 and HLA‐B*15:21 carrier status significantly increases the risk of carbamazepine‐induced nonimmediate cADR.
Warit Ruanglertboon +11 more
wiley +1 more source
Carbamazepine-Induced Toxic Epidermal Necrolysis
Journal of Integrated Health Sciences, 2018 Toxic epidermal necrolysis (TEN) is an uncommon; however, life-threatening dermatological condition which occurs most frequently by the use of drugs. Some group of medications, such as antiepileptics, antibiotics as well as antivirals, can induce such ...
Kushal Gohel +3 more
doaj +1 more source
Genetic and Immune Predictors for Hypersensitivity Syndrome to Antiepileptic Drugs [PDF]
, 2011 Hypersensitivity syndrome reactions (HSR) to antiepileptic drugs (AED) are associated with severe clinical cutaneous adverse reactions (SCAR).Our aims are: to assess HSRs to AEDs using the in vitro lymphocyte toxicity assay (LTA) in patients who ...
Lawrence Cohen +3 more
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