Results 51 to 60 of about 11,471 (211)
Ciprofloxacin, among the many Fluoroquinolones, has been widely used as a broad‐spectrum antibiotic due to its wide range of action and relatively safe adverse effect profile.
Bishal Dhakal +7 more
doaj +1 more source
Population Genomics Insights into Pharmacogenomic Differentiation Between East Asians and Europeans
Genetic variation contributes substantially to interindividual and interpopulation differences in drug response, yet most pharmacogenomic studies remain biased toward European populations. Here, we systematically assessed pharmacogenomic variation across East Asians (EAS) and Europeans (EUR) using public genomic datasets and investigated the potential ...
Sihan Chen, Hongpu Chen, Shuhua Xu
wiley +1 more source
ABSTRACT Immune checkpoint inhibitor (ICI)‐driven alterations in the immune system can induce immune‐related adverse events (irAEs). Cutaneous irAEs are notable for being the most common and for their early onset; however, the risk factors underlying their development and severity remain unclear. In this study, we retrospectively analyzed 1224 Japanese
Tomoya Watanabe +4 more
wiley +1 more source
ABSTRACT The present guideline updates the initial ESCD patch testing guideline, summarizing all aspects of patch testing for the diagnosis of contact allergy in patients suspected of suffering, or having been suffering, from allergic contact dermatitis or other delayed‐type hypersensitivity skin and mucosal conditions. Sections with brief descriptions
Wolfgang Uter +23 more
wiley +1 more source
Letter in Reply: Important Points in Toxic Epidermal Necrolysis Management
Classically, toxic epidermal necrolysis (TEN) is considered as part of a group of cutaneous hypersensitivity reaction with a spectrum of severity, erythema multiforme (EM) followed by Stevens-Johnson syndrome (SJS), and TEN.
Lutfi Al-Kathiri
doaj +1 more source
Epidermal necrolysis: SCORTEN performance in AIDS and non-AIDS patients [PDF]
: Background: Stevens-Johnson syndrome and toxic epidermal necrolysis are life-threatening blistering drug reactions with high incidence of ocular sequela.
Carlos Gustavo Wambier +8 more
doaj +1 more source
Stevens Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are rare, acute conditions, potentially life-threatening, immune-mediated and often unpredictable.
Martyna Rozenbajgier +3 more
doaj +1 more source
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti +7 more
wiley +1 more source
Fatal Phenytoin-Related Toxic Epidermal Necrolysis: Case Report
Toxic epidermal necrolysis is a rare but often fatal hypersensitivity reaction to numerous agents, including most anticonvulsants. The authors present a case of fatal phenytoin-related toxic epidermal necrolysis in a patient who was given prophylactic ...
Daniel F. Kelly, Donald G. Hope
core +1 more source

