Results 81 to 90 of about 205,640 (266)

Effects of honeybee (Apis cerana) visiting behaviour on toxic plant (Tripterygium hypoglaucum) reproduction. [PDF]

AoB Plants, 2022
Chen S, Wang Y, Li Y, Zhang X, Wu J.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Hormesis as a Particular Type of Plant Stress Response

Plants
Plants are continuously exposed to various abiotic and biotic stress factors, which influence their growth, productivity, and ecological fitness. This paper clarifies the concept of hormesis as a distinct low-dose stress response to toxic substances and ...
Agnieszka Siemieniuk, Małgorzata Rudnicka, Gabriela Jemioła, Eugeniusz Małkowski   +3 more
doaj   +1 more source

Insect Gut Isolate Pseudomonas sp. Strain Nvir Degrades the Toxic Plant Metabolite Nitropropionic Acid. [PDF]

Appl Environ Microbiol, 2022
Rogowska-van der Molen MA, Nagornîi D, Coolen S, de Graaf RM, Berben T, van Alen T, Janssen MACH, Rutjes FPJT, Jansen RS, Welte CU.   +9 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Editorial: Toxic Plant Proteins as Experimental Drugs for Human Pathologies. [PDF]

Front Pharmacol, 2021
Polito L, Bortolotti M, Iglesias R, Bolognesi A.   +3 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Extracts Prepared from a Canadian Toxic Plant Induce Light-Dependent Perinuclear Vacuoles in Human Cells. [PDF]

Toxins (Basel), 2021
Tuescher JM, Beck CR, Spencer L, Yeremy B, Shi Y, Andersen RJ, Golsteyn RM.   +6 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Deciphering seed dispersal decisions: Size, not tannin content, drives seed fate and survival in a tropical forest

Ecosphere, 2019
Scatter‐hoarding animals can dramatically affect plant survival by depositing seeds in favorable microhabitats away from parent plants (seed dispersal) and by consuming seeds (seed predation).
Erin K. Kuprewicz, Carlos García‐Robledo   +1 more
doaj   +1 more source