Results 111 to 120 of about 576,582 (313)

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Brine Shrimp Toxicity Evaluation of Some Tanzanian Plants Used Traditionally for the Treatment of Fungal Infections. [PDF]

open access: yes, 2006
Plants which are used by traditional healers in Tanzania have been evaluated to obtain preliminary data of their toxicity using the brine shrimps test. The results indicate that 9 out of 44 plant species whose extracts were tested exhibited high toxicity
Hamza, Omar J M   +10 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Root exudates enhanced rhizobacteria complexity and microbial carbon metabolism of toxic plants. [PDF]

open access: yesiScience, 2022
Wang W   +12 more
europepmc   +1 more source

Efecto de altas concentraciones de arsénico y flúor en el suelo sobre plantas de soja [PDF]

open access: yes, 2015
Arsénico (As) y Fluor (F) están presentes en muchos suelos, afectando a los cultivos y presentando riesgos en la cadena alimenticia. Nosotros llevamos a cabo un experimento en macetas con suelo enriquecido en ambos elementos, en un amplio rango de ...
Balestrasse, Karina Beatriz   +2 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Aquatic plants for removal of mevinphos from the aquatic environment [PDF]

open access: yes
Fragrant waterlily (Nymphaea odorata, Ait.), joint-grass (Paspalum distichum L.), and rush (Juncus repens, Michx.) were used to evaluate the effectiveness of vascular aquatic plants in removing the insecticide mevinphos (dimethyl-1-carbomethoxy-1propen-2-
Wolverton, B. C.
core   +1 more source

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