Results 101 to 110 of about 3,132,425 (322)

Sources, occurrence and toxic effects of emerging per- and polyfluoroalkyl substances (PFAS).

open access: yesNeurotoxicology and Teratology, 2023
Y. Manojkumar   +3 more
semanticscholar   +1 more source

Naturally toxic: natural substances used in personal care products

open access: yesEnvironmental Sciences Europe, 2015
BackgroundNature offers an incredible diversity of chemical compounds that boast a wide array of physiological effects. Many natural substances are employed in personal care products. Which of these natural substances are hazardous ingredients?
U. Klaschka
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Bisphenol M exposure promotes adiposity in mice via disrupting hepatic metabolism and gut microbiota homeostasis

open access: yesEcotoxicology and Environmental Safety
Bisphenol M (BPM), a structural analog of bisphenol A (BPA) commonly used in food packaging and consumer plastics, remains incompletely characterized in terms of its obesogenic potential and underlying molecular mechanisms, posing challenges for evidence-
Xin Wang   +6 more
doaj   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Light intensity can significantly regulate cadmium transformation into CdS nanoparticles in microalgae (Dunaliella salina and Phaeodactylum tricornutum)

open access: yesEcotoxicology and Environmental Safety
Light is a critical factor influencing algal growth and contributes to the uptake of metal elements by algae. However, the impact of light on the bioavailability and transformation of heavy metals requires further exploration, particularly in the context
Chang Shi   +7 more
doaj   +1 more source

TOXIC SUBSTANCES PRODUCED BY PNEUMOCOCCUS [PDF]

open access: yesJournal of Experimental Medicine, 1912
1. The filtered blood serum of rabbits infected with pneumococci is not toxic. 2. Extracts of pneumococci prepared by keeping emulsions of the bacteria in salt solution at 37° C. for varying periods of time may be toxic, and when injected intravenously into guinea pigs, may produce a train of symptoms followed by acute death resembling ...
openaire   +2 more sources

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

open access: yesMolecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern   +7 more
wiley   +1 more source

The Law of Toxic Substances [PDF]

open access: yesEnvironmental Health Perspectives, 1979
The law of toxic substances dates back to Medieval England, but the present comprehensive federal regulatory scheme was developed over the past two decades. This article presents a brief overview of the federal law of air and water pollution, solid waste control, and the regulation of chemicals.
openaire   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

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