Results 171 to 180 of about 2,950,586 (348)

Time toxicity during palliative chemotherapy for advanced malignancies: a prospective study. [PDF]

BMJ Support Palliat Care
Mailankody S, Kotian D, Udupa KS, Pai A, Shetty P, Guddattu V, Ganesan P.   +6 more
europepmc   +1 more source

Occurrence and toxicity of antibiotics in the aquatic environment: A review.

Chemosphere, 2020
Pavla Kovaláková, L. Cizmas, T. McDonald, B. Maršálek, Mingbao Feng, V. Sharma   +5 more
semanticscholar   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Digoxin Toxicity at Standard Doses in a Child with Subclinical Elevation of Thyrotrophin: A Case Report. [PDF]

Drug Healthc Patient Saf
Khorgami M, Dalili M, Karimian B.
europepmc   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Economic Evaluation of a Novel MicroRNA-Based Assay to Determine Risk of Late Genitourinary Radiation Toxicity in Patients With Prostate Cancer. [PDF]

J Health Econ Outcomes Res
Cooper JT, Schneider JE.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Informing the Borrowing Process for Dose-Finding Trials by Estimating the Similarity Between Population-Specific Dose-Toxicity Curves. [PDF]

Pharm Stat
Zocholl D, Götte H, Habermehl C, Günhan BK.   +3 more
europepmc   +1 more source

Severe amnestic syndrome due to theophylline toxicity

, 2021
Eimear Joyce, Diana A. Olszewska, Shane Davy, Timothy J. Counihan   +3 more
openalex   +2 more sources

Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study.

Journal of the American Medical Association (JAMA), 2000
F. Silverstein, G. Faich, J. Goldstein, L. Simon, T. Pincus, A. Whelton, R. Makuch, G. Eisen, N. Agrawal, W. Stenson, A. Burr, William W. Zhao, J. Kent, J. Lefkowith, K. Verburg, G. Geis   +15 more
semanticscholar   +1 more source